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Related entries of code: 1pw6
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1m48RCSB PDB    PDBbind133aa, >1M48:B|PDBID|CHAIN|... at 100%
1py2RCSB PDB    PDBbind132aa, >1PY2:D|PDBID|CHAIN|... at 100%
1z92RCSB PDB    PDBbind133aa, >1Z92:A|PDBID|CHAIN|... at 100%
2b5iRCSB PDB    PDBbind133aa, >2B5I:A|PDBID|CHAIN|... at 100%
2erjRCSB PDB    PDBbind133aa, >2ERJ:H|PDBID|CHAIN|... at 99%
5lqbRCSB PDB    PDBbind132aa, >5LQB:A|PDBID|CHAIN|... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID1pw6
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Nameinterleukin-2
Ligand NameFRB
EC.Number E.C.-.-.-.-
Resolution 2.6(Å)
Affinity (Kd/Ki/IC50)IC50=6uM
Release Year2004
Protein/NA SequenceCheck fasta file
Primary ReferenceJ.Am.Chem.Soc. v125 pp. 15280-1, 2003
Ligand Properties
Formula C25H34Cl2N7O2
Molecular Weight 535.489
Exact Mass 534.215
No. of atoms 70
No. of bonds 73
Polar Surface Area 141.73
LOGP Value 5.71      (Computed with XLOGP3)
3.24      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 9
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P60568  
Entrez Gene IDNCBI Entrez Gene ID: 3558  
ASDInformation of known allosteric effects of PDB entries

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