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Related entries of code: 1xkk
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2itoRCSB PDB    PDBbind327aa, >2ITO:A|PDBID|CHAIN|... at 99%
2itpRCSB PDB    PDBbind327aa, >2ITP:A|PDBID|CHAIN|... at 99%
2ittRCSB PDB    PDBbind327aa, >2ITT:A|PDBID|CHAIN|... at 99%
2ityRCSB PDB    PDBbind327aa, >2ITY:A|PDBID|CHAIN|... at 100%
2itzRCSB PDB    PDBbind327aa, >2ITZ:A|PDBID|CHAIN|... at 99%
2j6mRCSB PDB    PDBbind327aa, >2J6M:A|PDBID|CHAIN|... at 100%
2jiuRCSB PDB    PDBbind328aa, >2JIU:B|PDBID|CHAIN|... at 99%
2rgpRCSB PDB    PDBbind315aa, >2RGP:A|PDBID|CHAIN|... at 100%
3belRCSB PDB    PDBbind315aa, >3BEL:A|PDBID|CHAIN|... at 100%
3ikaRCSB PDB    PDBbind331aa, >3IKA:B|PDBID|CHAIN|... at 98%
3pozRCSB PDB    PDBbind327aa, >3POZ:A|PDBID|CHAIN|... at 100%
3ug2RCSB PDB    PDBbind334aa, >3UG2:A|PDBID|CHAIN|... at 97%
3w2oRCSB PDB    PDBbind331aa, >3W2O:A|PDBID|CHAIN|... at 99%
3w2pRCSB PDB    PDBbind331aa, >3W2P:A|PDBID|CHAIN|... at 99%
3w2qRCSB PDB    PDBbind331aa, >3W2Q:A|PDBID|CHAIN|... at 99%
3w2rRCSB PDB    PDBbind331aa, >3W2R:A|PDBID|CHAIN|... at 99%
3w2sRCSB PDB    PDBbind330aa, >3W2S:A|PDBID|CHAIN|... at 99%
3w32RCSB PDB    PDBbind330aa, >3W32:A|PDBID|CHAIN|... at 99%
3w33RCSB PDB    PDBbind330aa, >3W33:A|PDBID|CHAIN|... at 99%
4jq7RCSB PDB    PDBbind328aa, >4JQ7:A|PDBID|CHAIN|... at 99%
4jq8RCSB PDB    PDBbind328aa, >4JQ8:A|PDBID|CHAIN|... at 99%
4jr3RCSB PDB    PDBbind328aa, >4JR3:A|PDBID|CHAIN|... at 99%
4jrvRCSB PDB    PDBbind328aa, >4JRV:A|PDBID|CHAIN|... at 99%
4li5RCSB PDB    PDBbind328aa, >4LI5:A|PDBID|CHAIN|... at 99%
4rj4RCSB PDB    PDBbind331aa, >4RJ4:A|PDBID|CHAIN|... at 97%
4rj5RCSB PDB    PDBbind331aa, >4RJ5:A|PDBID|CHAIN|... at 97%
4rj6RCSB PDB    PDBbind331aa, >4RJ6:A|PDBID|CHAIN|... at 97%
4rj7RCSB PDB    PDBbind331aa, >4RJ7:A|PDBID|CHAIN|... at 97%
4rj8RCSB PDB    PDBbind331aa, >4RJ8:A|PDBID|CHAIN|... at 97%
5c8kRCSB PDB    PDBbind331aa, >5C8K:A|PDBID|CHAIN|... at 97%
5c8mRCSB PDB    PDBbind331aa, >5C8M:A|PDBID|CHAIN|... at 97%
5c8nRCSB PDB    PDBbind331aa, >5C8N:A|PDBID|CHAIN|... at 97%
5calRCSB PDB    PDBbind331aa, >5CAL:A|PDBID|CHAIN|... at 97%
5canRCSB PDB    PDBbind331aa, >5CAN:A|PDBID|CHAIN|... at 97%
5caoRCSB PDB    PDBbind331aa, >5CAO:A|PDBID|CHAIN|... at 97%
5capRCSB PDB    PDBbind331aa, >5CAP:A|PDBID|CHAIN|... at 97%
5caqRCSB PDB    PDBbind331aa, >5CAQ:A|PDBID|CHAIN|... at 97%
5casRCSB PDB    PDBbind331aa, >5CAS:A|PDBID|CHAIN|... at 97%
5cauRCSB PDB    PDBbind331aa, >5CAU:A|PDBID|CHAIN|... at 97%
5cavRCSB PDB    PDBbind331aa, >5CAV:A|PDBID|CHAIN|... at 99%
5edqRCSB PDB    PDBbind331aa, >5EDQ:A|PDBID|CHAIN|... at 97%
5edrRCSB PDB    PDBbind331aa, >5EDR:A|PDBID|CHAIN|... at 97%
5em5RCSB PDB    PDBbind331aa, >5EM5:A|PDBID|CHAIN|... at 97%
5em6RCSB PDB    PDBbind331aa, >5EM6:A|PDBID|CHAIN|... at 97%
5em7RCSB PDB    PDBbind331aa, >5EM7:A|PDBID|CHAIN|... at 97%
5em8RCSB PDB    PDBbind331aa, >5EM8:A|PDBID|CHAIN|... at 99%
5hcxRCSB PDB    PDBbind331aa, >5HCX:A|PDBID|CHAIN|... at 97%
5hcyRCSB PDB    PDBbind331aa, >5HCY:A|PDBID|CHAIN|... at 97%
5hg5RCSB PDB    PDBbind329aa, >5HG5:A|PDBID|CHAIN|... at 99%
5hg7RCSB PDB    PDBbind329aa, >5HG7:A|PDBID|CHAIN|... at 99%
5hg8RCSB PDB    PDBbind329aa, >5HG8:A|PDBID|CHAIN|... at 99%
5hg9RCSB PDB    PDBbind329aa, >5HG9:A|PDBID|CHAIN|... at 99%
5j9yRCSB PDB    PDBbind323aa, >5J9Y:A|PDBID|CHAIN|... at 99%
5j9zRCSB PDB    PDBbind325aa, >5J9Z:A|PDBID|CHAIN|... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3bbtRCSB PDB    PDBbindFMM

Entry Information
PDB ID1xkk
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein Nameepidermal growth factor receptor
Ligand NameFMM
EC.Number E.C.
Resolution 2.4(Å)
Affinity (Kd/Ki/IC50)Ki=3nM
Release Year2004
Protein/NA SequenceCheck fasta file
Primary ReferenceCancer Res. v64 pp. 6652-9, 2004
Ligand Properties
Formula C29H27ClFN4O4S
Molecular Weight 582.065
Exact Mass 581.143
No. of atoms 67
No. of bonds 71
Polar Surface Area 119.31
LOGP Value 5.12      (Computed with XLOGP3)
6.27      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 11
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P00533  
Entrez Gene IDNCBI Entrez Gene ID: 1956  
ASDInformation of known allosteric effects of PDB entries

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