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Related entries of code: 1owk
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1gj7RCSB PDB    PDBbind253aa, >1GJ7:B|PDBID|CHAIN|... at 99%
1gj8RCSB PDB    PDBbind253aa, >1GJ8:B|PDBID|CHAIN|... at 99%
1gjaRCSB PDB    PDBbind253aa, >1GJA:B|PDBID|CHAIN|... at 99%
1gjbRCSB PDB    PDBbind253aa, >1GJB:B|PDBID|CHAIN|... at 99%
1c5xRCSB PDB    PDBbind253aa, >1C5X:B|PDBID|CHAIN|... at 99%
1c5yRCSB PDB    PDBbind253aa, >1C5Y:B|PDBID|CHAIN|... at 99%
1c5zRCSB PDB    PDBbind253aa, >1C5Z:B|PDBID|CHAIN|... at 99%
1ejnRCSB PDB    PDBbind253aa, >1EJN:A|PDBID|CHAIN|... at 99%
1f5kRCSB PDB    PDBbind253aa, >1F5K:U|PDBID|CHAIN|... at 99%
1f5lRCSB PDB    PDBbind253aa, >1F5L:A|PDBID|CHAIN|... at 99%
1f92RCSB PDB    PDBbind253aa, >1F92:A|PDBID|CHAIN|... at 99%
1fv9RCSB PDB    PDBbind245aa, >1FV9:A|PDBID|CHAIN|... at 99%
1gi7RCSB PDB    PDBbind245aa, >1GI7:B|PDBID|CHAIN|... at 99%
1gi8RCSB PDB    PDBbind245aa, >1GI8:B|PDBID|CHAIN|... at 99%
1gi9RCSB PDB    PDBbind245aa, >1GI9:B|PDBID|CHAIN|... at 99%
1gjcRCSB PDB    PDBbind253aa, >1GJC:B|PDBID|CHAIN|... at 99%
1gjdRCSB PDB    PDBbind253aa, >1GJD:B|PDBID|CHAIN|... at 99%
1o3pRCSB PDB    PDBbind253aa, >1O3P:B|PDBID|CHAIN|... at 99%
1o5aRCSB PDB    PDBbind253aa, >1O5A:B|PDBID|CHAIN|... at 99%
1o5bRCSB PDB    PDBbind253aa, >1O5B:B|PDBID|CHAIN|... at 99%
1o5cRCSB PDB    PDBbind253aa, >1O5C:B|PDBID|CHAIN|... at 99%
1owdRCSB PDB    PDBbind245aa, >1OWD:A|PDBID|CHAIN|... at 100%
1oweRCSB PDB    PDBbind245aa, >1OWE:A|PDBID|CHAIN|... at 99%
1owhRCSB PDB    PDBbind245aa, >1OWH:A|PDBID|CHAIN|... at 99%
1owiRCSB PDB    PDBbind245aa, >1OWI:A|PDBID|CHAIN|... at 100%
1owjRCSB PDB    PDBbind245aa, >1OWJ:A|PDBID|CHAIN|... at 100%
1sc8RCSB PDB    PDBbind262aa, >1SC8:U|PDBID|CHAIN|... at 99%
1sqaRCSB PDB    PDBbind245aa, >1SQA:A|PDBID|CHAIN|... at 99%
1sqoRCSB PDB    PDBbind245aa, >1SQO:A|PDBID|CHAIN|... at 99%
1sqtRCSB PDB    PDBbind245aa, >1SQT:A|PDBID|CHAIN|... at 100%
1u6qRCSB PDB    PDBbind245aa, >1U6Q:A|PDBID|CHAIN|... at 100%
1vj9RCSB PDB    PDBbind262aa, >1VJ9:U|PDBID|CHAIN|... at 99%
1vjaRCSB PDB    PDBbind262aa, >1VJA:U|PDBID|CHAIN|... at 99%
1w0zRCSB PDB    PDBbind247aa, >1W0Z:U|PDBID|CHAIN|... at 99%
1w10RCSB PDB    PDBbind247aa, >1W10:U|PDBID|CHAIN|... at 99%
1w11RCSB PDB    PDBbind247aa, >1W11:U|PDBID|CHAIN|... at 99%
1w12RCSB PDB    PDBbind247aa, >1W12:U|PDBID|CHAIN|... at 99%
1w13RCSB PDB    PDBbind247aa, >1W13:U|PDBID|CHAIN|... at 99%
1w14RCSB PDB    PDBbind247aa, >1W14:U|PDBID|CHAIN|... at 99%
2vntRCSB PDB    PDBbind276aa, >2VNT:F|PDBID|CHAIN|... at 100%
2r2wRCSB PDB    PDBbind253aa, >2R2W:U|PDBID|CHAIN|... at 99%
2vinRCSB PDB    PDBbind253aa, >2VIN:A|PDBID|CHAIN|... at 99%
2vioRCSB PDB    PDBbind253aa, >2VIO:A|PDBID|CHAIN|... at 99%
2vipRCSB PDB    PDBbind253aa, >2VIP:A|PDBID|CHAIN|... at 99%
2viqRCSB PDB    PDBbind253aa, >2VIQ:A|PDBID|CHAIN|... at 99%
2vivRCSB PDB    PDBbind253aa, >2VIV:A|PDBID|CHAIN|... at 99%
2viwRCSB PDB    PDBbind253aa, >2VIW:A|PDBID|CHAIN|... at 99%
3khvRCSB PDB    PDBbind253aa, >3KHV:A|PDBID|CHAIN|... at 98%
3kidRCSB PDB    PDBbind253aa, >3KID:U|PDBID|CHAIN|... at 98%
3ig6RCSB PDB    PDBbind253aa, >3IG6:D|PDBID|CHAIN|... at 99%
3kgpRCSB PDB    PDBbind253aa, >3KGP:A|PDBID|CHAIN|... at 98%
3mhwRCSB PDB    PDBbind247aa, >3MHW:U|PDBID|CHAIN|... at 99%
4h42RCSB PDB    PDBbind248aa, >4H42:U|PDBID|CHAIN|... at 98%
4mnvRCSB PDB    PDBbind245aa, >4MNV:A|PDBID|CHAIN|... at 98%
4x1nRCSB PDB    PDBbind247aa, >4X1N:U|PDBID|CHAIN|... at 98%
4x1pRCSB PDB    PDBbind247aa, >4X1P:U|PDBID|CHAIN|... at 98%
4x1qRCSB PDB    PDBbind247aa, >4X1Q:U|PDBID|CHAIN|... at 98%
4x1rRCSB PDB    PDBbind247aa, >4X1R:U|PDBID|CHAIN|... at 98%
4x1sRCSB PDB    PDBbind247aa, >4X1S:U|PDBID|CHAIN|... at 98%
4zhlRCSB PDB    PDBbind247aa, >4ZHL:U|PDBID|CHAIN|... at 98%
4zhmRCSB PDB    PDBbind247aa, >4ZHM:U|PDBID|CHAIN|... at 98%
5xg4RCSB PDB    PDBbind246aa, >5XG4:U|PDBID|CHAIN|... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID1owk
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Nameurokinase-type plasminogen activator
Ligand Name303
EC.Number E.C.3.4.21.73
Resolution 2.8(Å)
Affinity (Kd/Ki/IC50)Ki=23.5nM
Release Year2003
Protein/NA SequenceCheck fasta file
Primary ReferenceJ.Med.Chem. v47 pp. 303-24, 2004
Ligand Properties
Formula C24H28N4O
Molecular Weight 388.505
Exact Mass 388.226
No. of atoms 57
No. of bonds 60
Polar Surface Area 97.32
LOGP Value 5.56      (Computed with XLOGP3)
3.72      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 1
No. of Rotatable Bonds: 5
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P00749  
Entrez Gene IDNCBI Entrez Gene ID: 5328  
ASDInformation of known allosteric effects of PDB entries

 
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