Related entries of code: 2itp
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1xkkRCSB PDB    PDBbind352aa, >1xkk_A... at 94%
2itoRCSB PDB    PDBbind327aa, >2ito_A... at 99%
2ittRCSB PDB    PDBbind327aa, >2itt_A... at 99%
2ityRCSB PDB    PDBbind327aa, >2ity_A... at 99%
2itzRCSB PDB    PDBbind327aa, >2itz_A... at 99%
2j6mRCSB PDB    PDBbind327aa, >2j6m_A... at 99%
2jiuRCSB PDB    PDBbind328aa, >2jiu_B... at 99%
2rgpRCSB PDB    PDBbind315aa, >2rgp_A... at 99%
3belRCSB PDB    PDBbind315aa, >3bel_A... at 99%
3ikaRCSB PDB    PDBbind331aa, >3ika_B... at 98%
3pozRCSB PDB    PDBbind327aa, >3poz_A... at 99%
3ug2RCSB PDB    PDBbind334aa, >3ug2_A... at 97%
3w2oRCSB PDB    PDBbind331aa, >3w2o_A... at 97%
3w2pRCSB PDB    PDBbind331aa, >3w2p_A... at 97%
3w2qRCSB PDB    PDBbind331aa, >3w2q_A... at 97%
3w2rRCSB PDB    PDBbind331aa, >3w2r_A... at 97%
3w2sRCSB PDB    PDBbind330aa, >3w2s_A... at 98%
3w32RCSB PDB    PDBbind330aa, >3w32_A... at 98%
3w33RCSB PDB    PDBbind330aa, >3w33_A... at 98%
4jq7RCSB PDB    PDBbind328aa, >4jq7_A... at 99%
4jq8RCSB PDB    PDBbind328aa, >4jq8_A... at 99%
4jr3RCSB PDB    PDBbind328aa, >4jr3_A... at 99%
4jrvRCSB PDB    PDBbind328aa, >4jrv_A... at 99%
4li5RCSB PDB    PDBbind328aa, >4li5_A... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
2ittRCSB PDB    PDBbindAEE
2j6mRCSB PDB    PDBbindAEE
2jiuRCSB PDB    PDBbindAEE

Entry Information
PDB ID2itp
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Nameepidermal growth factor receptor(EGFR) kinase domain G719S mutation
Ligand NameAEE
EC.Number E.C.2.7.10.1
Resolution 2.74(Å)
Affinity (Kd/Ki/IC50)Kd=11.3nM
Release Year2007
Protein/NA SequenceCheck fasta file
Primary Reference(2007) Cancer Cell Vol. 11: pp. 217

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
ASDInformation of known allosteric effects of PDB entries

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