Related entries of code: 2xfk
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1fknRCSB PDB    PDBbind391aa, >1fkn_B... at 100%
1m4hRCSB PDB    PDBbind391aa, >1m4h_B... at 100%
1tqfRCSB PDB    PDBbind405aa, >1tqf_A... at 99%
1xs7RCSB PDB    PDBbind389aa, >1xs7_D... at 100%
1ym2RCSB PDB    PDBbind402aa, >1ym2_C... at 99%
1ym4RCSB PDB    PDBbind408aa, >1ym4_C... at 99%
2b8lRCSB PDB    PDBbind405aa, >2b8l_A... at 99%
2b8vRCSB PDB    PDBbind405aa, >2b8v_A... at 99%
2f3eRCSB PDB    PDBbind402aa, >2f3e_C... at 99%
2f3fRCSB PDB    PDBbind402aa, >2f3f_C... at 99%
2fdpRCSB PDB    PDBbind388aa, >2fdp_C... at 100%
2g94RCSB PDB    PDBbind389aa, >2g94_D... at 100%
2hizRCSB PDB    PDBbind455aa, >2hiz_C... at 100%
2hm1RCSB PDB    PDBbind406aa, >2hm1_A... at 97%
2iqgRCSB PDB    PDBbind406aa, >2iqg_A... at 97%
2irzRCSB PDB    PDBbind405aa, >2irz_A... at 99%
2is0RCSB PDB    PDBbind405aa, >2is0_A... at 99%
2oahRCSB PDB    PDBbind405aa, >2oah_A... at 99%
2ohmRCSB PDB    PDBbind402aa, >2ohm_A... at 99%
2ohpRCSB PDB    PDBbind402aa, >2ohp_A... at 99%
2ohqRCSB PDB    PDBbind402aa, >2ohq_A... at 99%
2ohrRCSB PDB    PDBbind402aa, >2ohr_A... at 99%
2ohsRCSB PDB    PDBbind402aa, >2ohs_A... at 99%
2ohtRCSB PDB    PDBbind402aa, >2oht_A... at 99%
2ohuRCSB PDB    PDBbind402aa, >2ohu_A... at 99%
2qp8RCSB PDB    PDBbind395aa, >2qp8_B... at 99%
2qu2RCSB PDB    PDBbind415aa, >2qu2_A... at 98%
2qu3RCSB PDB    PDBbind415aa, >2qu3_A... at 98%
2viyRCSB PDB    PDBbind392aa, >2viy_A... at 98%
2vizRCSB PDB    PDBbind392aa, >2viz_A... at 98%
2vj6RCSB PDB    PDBbind392aa, >2vj6_A... at 98%
2vj7RCSB PDB    PDBbind392aa, >2vj7_A... at 98%
2vj9RCSB PDB    PDBbind392aa, >2vj9_A... at 98%
2vkmRCSB PDB    PDBbind389aa, >2vkm_D... at 100%
2p4jRCSB PDB    PDBbind389aa, >2p4j_D... at 100%
2p83RCSB PDB    PDBbind455aa, >2p83_C... at 100%
2p8hRCSB PDB    PDBbind405aa, >2p8h_A... at 99%
2ph6RCSB PDB    PDBbind405aa, >2ph6_A... at 99%
2ph8RCSB PDB    PDBbind405aa, >2ph8_A... at 99%
2q11RCSB PDB    PDBbind388aa, >2q11_C... at 98%
2q15RCSB PDB    PDBbind385aa, >2q15_A... at 98%
2qk5RCSB PDB    PDBbind395aa, >2qk5_B... at 99%
2qmdRCSB PDB    PDBbind395aa, >2qmd_B... at 99%
2qmfRCSB PDB    PDBbind395aa, >2qmf_B... at 99%
2qmgRCSB PDB    PDBbind395aa, >2qmg_B... at 99%
2qzkRCSB PDB    PDBbind405aa, >2qzk_A... at 99%
2qzlRCSB PDB    PDBbind411aa, >2qzl_A... at 97%
2va5RCSB PDB    PDBbind455aa, >2va5_A... at 99%
2va6RCSB PDB    PDBbind455aa, >2va6_A... at 99%
2va7RCSB PDB    PDBbind455aa, >2va7_A... at 99%
2vieRCSB PDB    PDBbind392aa, >2vie_A... at 98%
2vnmRCSB PDB    PDBbind392aa, >2vnm_A... at 98%
2vnnRCSB PDB    PDBbind392aa, >2vnn_A... at 98%
2wezRCSB PDB    PDBbind392aa, >2wez_A... at 98%
2wf0RCSB PDB    PDBbind392aa, >2wf0_A... at 98%
2wf1RCSB PDB    PDBbind392aa, >2wf1_A... at 98%
2wf2RCSB PDB    PDBbind392aa, >2wf2_A... at 98%
2wf3RCSB PDB    PDBbind392aa, >2wf3_A... at 98%
2wf4RCSB PDB    PDBbind392aa, >2wf4_A... at 98%
2xfiRCSB PDB    PDBbind392aa, >2xfi_A... at 98%
2xfjRCSB PDB    PDBbind392aa, >2xfj_A... at 98%
2zdzRCSB PDB    PDBbind415aa, >2zdz_A... at 98%
2ze1RCSB PDB    PDBbind415aa, >2ze1_A... at 98%
3cibRCSB PDB    PDBbind390aa, >3cib_B... at 100%
3cicRCSB PDB    PDBbind390aa, >3cic_B... at 100%
3cidRCSB PDB    PDBbind390aa, >3cid_B... at 100%
3braRCSB PDB    PDBbind409aa, >3bra_A... at 99%
3bufRCSB PDB    PDBbind409aa, >3buf_A... at 99%
3bugRCSB PDB    PDBbind409aa, >3bug_A... at 99%
3buhRCSB PDB    PDBbind409aa, >3buh_A... at 99%
3ckpRCSB PDB    PDBbind412aa, >3ckp_C... at 99%
3ckrRCSB PDB    PDBbind412aa, >3ckr_C... at 99%
3dm6RCSB PDB    PDBbind406aa, >3dm6_C... at 99%
3duyRCSB PDB    PDBbind402aa, >3duy_C... at 99%
3dv1RCSB PDB    PDBbind402aa, >3dv1_C... at 99%
3dv5RCSB PDB    PDBbind402aa, >3dv5_C... at 99%
3exoRCSB PDB    PDBbind413aa, >3exo_A... at 99%
3fktRCSB PDB    PDBbind405aa, >3fkt_A... at 99%
3h0bRCSB PDB    PDBbind405aa, >3h0b_C... at 99%
3hvgRCSB PDB    PDBbind411aa, >3hvg_C... at 99%
3hw1RCSB PDB    PDBbind411aa, >3hw1_C... at 99%
3i25RCSB PDB    PDBbind406aa, >3i25_C... at 99%
3igbRCSB PDB    PDBbind415aa, >3igb_A... at 98%
3in3RCSB PDB    PDBbind415aa, >3in3_A... at 98%
3in4RCSB PDB    PDBbind415aa, >3in4_A... at 98%
3indRCSB PDB    PDBbind415aa, >3ind_A... at 98%
3ineRCSB PDB    PDBbind415aa, >3ine_A... at 98%
3infRCSB PDB    PDBbind415aa, >3inf_A... at 98%
3inhRCSB PDB    PDBbind415aa, >3inh_A... at 98%
3ivhRCSB PDB    PDBbind406aa, >3ivh_A... at 97%
3iviRCSB PDB    PDBbind406aa, >3ivi_C... at 97%
3ixjRCSB PDB    PDBbind388aa, >3ixj_C... at 100%
3ixkRCSB PDB    PDBbind405aa, >3ixk_C... at 100%
3k5cRCSB PDB    PDBbind402aa, >3k5c_C... at 99%
3k5dRCSB PDB    PDBbind408aa, >3k5d_C... at 99%
3k5fRCSB PDB    PDBbind402aa, >3k5f_C... at 99%
3k5gRCSB PDB    PDBbind402aa, >3k5g_C... at 99%
3kmxRCSB PDB    PDBbind395aa, >3kmx_B... at 100%
3kmyRCSB PDB    PDBbind395aa, >3kmy_B... at 100%
3kn0RCSB PDB    PDBbind395aa, >3kn0_B... at 100%
3l38RCSB PDB    PDBbind415aa, >3l38_A... at 98%
3l3aRCSB PDB    PDBbind415aa, >3l3a_A... at 98%
3l58RCSB PDB    PDBbind414aa, >3l58_B... at 99%
3l59RCSB PDB    PDBbind414aa, >3l59_B... at 99%
3l5bRCSB PDB    PDBbind414aa, >3l5b_B... at 99%
3l5cRCSB PDB    PDBbind414aa, >3l5c_B... at 99%
3l5dRCSB PDB    PDBbind414aa, >3l5d_B... at 99%
3l5eRCSB PDB    PDBbind414aa, >3l5e_B... at 99%
3l5fRCSB PDB    PDBbind414aa, >3l5f_B... at 99%
3lhgRCSB PDB    PDBbind415aa, >3lhg_A... at 98%
3lnkRCSB PDB    PDBbind395aa, >3lnk_B... at 100%
3lpiRCSB PDB    PDBbind455aa, >3lpi_B... at 99%
3lpjRCSB PDB    PDBbind455aa, >3lpj_B... at 99%
3lpkRCSB PDB    PDBbind455aa, >3lpk_B... at 99%
3msjRCSB PDB    PDBbind411aa, >3msj_C... at 99%
3mskRCSB PDB    PDBbind408aa, >3msk_A... at 99%
3mslRCSB PDB    PDBbind408aa, >3msl_A... at 99%
3n4lRCSB PDB    PDBbind406aa, >3n4l_C... at 97%
3nshRCSB PDB    PDBbind406aa, >3nsh_C... at 97%
3ohfRCSB PDB    PDBbind455aa, >3ohf_B... at 99%
3ohhRCSB PDB    PDBbind455aa, >3ohh_B... at 99%
3oozRCSB PDB    PDBbind415aa, >3ooz_A... at 98%
3pi5RCSB PDB    PDBbind402aa, >3pi5_C... at 99%
3qbhRCSB PDB    PDBbind402aa, >3qbh_C... at 99%
4djyRCSB PDB    PDBbind414aa, >4djy_B... at 99%
3r2fRCSB PDB    PDBbind455aa, >3r2f_E... at 99%
3rsvRCSB PDB    PDBbind411aa, >3rsv_A... at 99%
3rsxRCSB PDB    PDBbind411aa, >3rsx_A... at 99%
3rthRCSB PDB    PDBbind411aa, >3rth_A... at 99%
3rtmRCSB PDB    PDBbind411aa, >3rtm_A... at 99%
3rtnRCSB PDB    PDBbind411aa, >3rtn_A... at 99%
3ru1RCSB PDB    PDBbind411aa, >3ru1_A... at 99%
3rviRCSB PDB    PDBbind411aa, >3rvi_A... at 99%
3s2oRCSB PDB    PDBbind408aa, >3s2o_A... at 99%
3s7lRCSB PDB    PDBbind415aa, >3s7l_A... at 98%
3s7mRCSB PDB    PDBbind415aa, >3s7m_A... at 98%
3skfRCSB PDB    PDBbind455aa, >3skf_B... at 99%
3skgRCSB PDB    PDBbind455aa, >3skg_E... at 99%
3tppRCSB PDB    PDBbind433aa, >3tpp_A... at 94%
3u6aRCSB PDB    PDBbind390aa, >3u6a_C... at 99%
3udhRCSB PDB    PDBbind404aa, >3udh_A... at 98%
3udjRCSB PDB    PDBbind404aa, >3udj_A... at 98%
3udkRCSB PDB    PDBbind404aa, >3udk_A... at 98%
3udmRCSB PDB    PDBbind404aa, >3udm_A... at 98%
3udnRCSB PDB    PDBbind404aa, >3udn_A... at 98%
3udpRCSB PDB    PDBbind404aa, >3udp_A... at 98%
3udqRCSB PDB    PDBbind404aa, >3udq_A... at 98%
3udrRCSB PDB    PDBbind404aa, >3udr_A... at 98%
3udyRCSB PDB    PDBbind404aa, >3udy_A... at 98%
3uflRCSB PDB    PDBbind389aa, >3ufl_A... at 100%
3uqpRCSB PDB    PDBbind433aa, >3uqp_A... at 94%
3uqrRCSB PDB    PDBbind433aa, >3uqr_C... at 94%
3veuRCSB PDB    PDBbind402aa, >3veu_A... at 99%
3vf3RCSB PDB    PDBbind402aa, >3vf3_A... at 99%
3vg1RCSB PDB    PDBbind402aa, >3vg1_A... at 99%
3vv6RCSB PDB    PDBbind416aa, >3vv6_A... at 98%
3vv7RCSB PDB    PDBbind416aa, >3vv7_A... at 98%
3vv8RCSB PDB    PDBbind416aa, >3vv8_A... at 98%
4acuRCSB PDB    PDBbind411aa, >4acu_A... at 99%
4acxRCSB PDB    PDBbind411aa, >4acx_A... at 99%
4azyRCSB PDB    PDBbind411aa, >4azy_A... at 99%
4b00RCSB PDB    PDBbind411aa, >4b00_A... at 99%
4b1cRCSB PDB    PDBbind375aa, >4b1c_A... at 99%
4b1dRCSB PDB    PDBbind388aa, >4b1d_A... at 100%
4d85RCSB PDB    PDBbind408aa, >4d85_A... at 99%
4d88RCSB PDB    PDBbind402aa, >4d88_A... at 99%
4d89RCSB PDB    PDBbind402aa, >4d89_A... at 99%
4dh6RCSB PDB    PDBbind411aa, >4dh6_A... at 99%
4di2RCSB PDB    PDBbind411aa, >4di2_C... at 99%
4djuRCSB PDB    PDBbind414aa, >4dju_B... at 99%
4djvRCSB PDB    PDBbind414aa, >4djv_B... at 99%
4djwRCSB PDB    PDBbind414aa, >4djw_B... at 99%
4djxRCSB PDB    PDBbind414aa, >4djx_B... at 99%
4dpfRCSB PDB    PDBbind391aa, >4dpf_A... at 99%
4dpiRCSB PDB    PDBbind391aa, >4dpi_A... at 99%
4dusRCSB PDB    PDBbind411aa, >4dus_A... at 99%
4ewoRCSB PDB    PDBbind386aa, >4ewo_A... at 100%
4exgRCSB PDB    PDBbind386aa, >4exg_A... at 100%
4fm7RCSB PDB    PDBbind404aa, >4fm7_A... at 98%
4fm8RCSB PDB    PDBbind404aa, >4fm8_A... at 98%
4friRCSB PDB    PDBbind411aa, >4fri_A... at 99%
4frjRCSB PDB    PDBbind411aa, >4frj_A... at 99%
4frkRCSB PDB    PDBbind411aa, >4frk_A... at 99%
4frsRCSB PDB    PDBbind395aa, >4frs_B... at 100%
4fseRCSB PDB    PDBbind455aa, >4fse_E... at 99%
4fslRCSB PDB    PDBbind412aa, >4fsl_E... at 99%
4gidRCSB PDB    PDBbind388aa, >4gid_D... at 100%
4h1eRCSB PDB    PDBbind414aa, >4h1e_B... at 99%
4h3fRCSB PDB    PDBbind414aa, >4h3f_B... at 99%
4h3gRCSB PDB    PDBbind414aa, >4h3g_B... at 99%
4h3iRCSB PDB    PDBbind414aa, >4h3i_B... at 99%
4h3jRCSB PDB    PDBbind414aa, >4h3j_B... at 99%
4ha5RCSB PDB    PDBbind414aa, >4ha5_B... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID2xfk
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameHuman beta-secretase 1
Ligand NameAA9
EC.Number E.C.3.4.23.46
Resolution 1.8(Å)
Affinity (Kd/Ki/IC50)IC50=3nM
Release Year2010
Protein/NA SequenceCheck fasta file
Primary Reference(2010) Bioorg.Med.Chem.Lett. Vol. 20: pp. 4639-4644

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
ASDInformation of known allosteric effects of PDB entries

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