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Related entries of code: 2xix
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1xwsRCSB PDB    PDBbind313aa, >1xws_A... at 100%
1yhsRCSB PDB    PDBbind273aa, >1yhs_A... at 100%
1yi3RCSB PDB    PDBbind273aa, >1yi3_A... at 100%
2c3iRCSB PDB    PDBbind313aa, >2c3i_B... at 99%
2j2iRCSB PDB    PDBbind312aa, >2j2i_B... at 99%
2o3pRCSB PDB    PDBbind293aa, >2o3p_A... at 97%
2o63RCSB PDB    PDBbind293aa, >2o63_A... at 97%
2o64RCSB PDB    PDBbind293aa, >2o64_A... at 97%
2o65RCSB PDB    PDBbind293aa, >2o65_A... at 97%
2objRCSB PDB    PDBbind333aa, >2obj_A... at 96%
2xiyRCSB PDB    PDBbind301aa, >2xiy_A... at 99%
2xizRCSB PDB    PDBbind301aa, >2xiz_A... at 99%
2xj0RCSB PDB    PDBbind301aa, >2xj0_A... at 99%
2xj1RCSB PDB    PDBbind301aa, >2xj1_A... at 99%
2xj2RCSB PDB    PDBbind301aa, >2xj2_A... at 99%
3bgpRCSB PDB    PDBbind333aa, >3bgp_A... at 96%
3bgqRCSB PDB    PDBbind333aa, >3bgq_A... at 96%
3bgzRCSB PDB    PDBbind333aa, >3bgz_A... at 96%
3bwfRCSB PDB    PDBbind313aa, >3bwf_A... at 99%
3c4eRCSB PDB    PDBbind273aa, >3c4e_D... at 100%
3dcvRCSB PDB    PDBbind328aa, >3dcv_A... at 96%
3f2aRCSB PDB    PDBbind300aa, >3f2a_A... at 100%
3jxwRCSB PDB    PDBbind294aa, >3jxw_A... at 96%
3jy0RCSB PDB    PDBbind294aa, >3jy0_A... at 96%
3jyaRCSB PDB    PDBbind294aa, >3jya_A... at 96%
3ma3RCSB PDB    PDBbind313aa, >3ma3_A... at 99%
3r00RCSB PDB    PDBbind299aa, >3r00_A... at 95%
3r01RCSB PDB    PDBbind299aa, >3r01_A... at 95%
3r02RCSB PDB    PDBbind299aa, >3r02_A... at 95%
3r04RCSB PDB    PDBbind299aa, >3r04_A... at 95%
3uixRCSB PDB    PDBbind298aa, >3uix_A... at 95%
3umwRCSB PDB    PDBbind298aa, >3umw_A... at 95%
3umxRCSB PDB    PDBbind298aa, >3umx_A... at 95%
3vbqRCSB PDB    PDBbind299aa, >3vbq_A... at 95%
3vbtRCSB PDB    PDBbind299aa, >3vbt_A... at 95%
3vbvRCSB PDB    PDBbind299aa, >3vbv_A... at 95%
3vbwRCSB PDB    PDBbind299aa, >3vbw_A... at 95%
3vbxRCSB PDB    PDBbind299aa, >3vbx_A... at 95%
3vbyRCSB PDB    PDBbind299aa, >3vby_A... at 95%
3vc4RCSB PDB    PDBbind299aa, >3vc4_A... at 95%
4a7cRCSB PDB    PDBbind308aa, >4a7c_A... at 92%
4aluRCSB PDB    PDBbind328aa, >4alu_A... at 95%
4alvRCSB PDB    PDBbind328aa, >4alv_A... at 95%
4alwRCSB PDB    PDBbind328aa, >4alw_A... at 95%
4bznRCSB PDB    PDBbind314aa, >4bzn_A... at 99%
4bzoRCSB PDB    PDBbind314aa, >4bzo_A... at 99%
4dtkRCSB PDB    PDBbind276aa, >4dtk_A... at 100%
4enxRCSB PDB    PDBbind298aa, >4enx_A... at 95%
4enyRCSB PDB    PDBbind298aa, >4eny_A... at 95%
4k0yRCSB PDB    PDBbind274aa, >4k0y_A... at 100%
4k18RCSB PDB    PDBbind277aa, >4k18_A... at 100%
4k1bRCSB PDB    PDBbind273aa, >4k1b_A... at 100%
4lm5RCSB PDB    PDBbind298aa, >4lm5_A... at 95%
4lmuRCSB PDB    PDBbind298aa, >4lmu_A... at 95%
4mbiRCSB PDB    PDBbind293aa, >4mbi_A... at 97%
4mblRCSB PDB    PDBbind293aa, >4mbl_A... at 97%
4n6yRCSB PDB    PDBbind328aa, >4n6y_A... at 96%
4n6zRCSB PDB    PDBbind328aa, >4n6z_A... at 96%
4n70RCSB PDB    PDBbind328aa, >4n70_A... at 96%
4rpvRCSB PDB    PDBbind410aa, >4rpv_A... *
4xhkRCSB PDB    PDBbind315aa, >4xhk_B... at 99%
4ty1RCSB PDB    PDBbind286aa, >4ty1_A... at 95%
4wrsRCSB PDB    PDBbind286aa, >4wrs_A... at 95%
4wsyRCSB PDB    PDBbind286aa, >4wsy_A... at 95%
4wt6RCSB PDB    PDBbind286aa, >4wt6_A... at 95%
4xh6RCSB PDB    PDBbind294aa, >4xh6_A... at 96%
5diaRCSB PDB    PDBbind299aa, >5dia_A... at 95%
5dgzRCSB PDB    PDBbind299aa, >5dgz_A... at 95%
5dhjRCSB PDB    PDBbind299aa, >5dhj_A... at 95%
5dwrRCSB PDB    PDBbind328aa, >5dwr_A... at 96%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID2xix
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NamePROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE PIM-1
Ligand NameXIX
EC.Number E.C.2.7.1.37
Resolution 2.4(Å)
Affinity (Kd/Ki/IC50)IC50>5000uM
Release Year2011
Protein/NA SequenceCheck fasta file
Primary Reference(2011) Acta Crystallogr.,Sect.D Vol. 67: pp. 156-166
Ligand Properties
Formula C2H5N5
Molecular Weight 99.095
Exact Mass 99.055
No. of atoms 12
No. of bonds 12
Polar Surface Area 93.61
LOGP Value -1.61      (Computed with XLOGP3)
0.13      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 0
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 1
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P11309  
Entrez Gene IDNCBI Entrez Gene ID: 5292  
ASDInformation of known allosteric effects of PDB entries

 
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