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Related entries of code: 2xvd
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2vwuRCSB PDB    PDBbind302aa, >2vwu_A... *
2vwvRCSB PDB    PDBbind302aa, >2vwv_A... at 100%
2vwwRCSB PDB    PDBbind302aa, >2vww_A... at 100%
2vwxRCSB PDB    PDBbind302aa, >2vwx_A... at 100%
2vwyRCSB PDB    PDBbind302aa, >2vwy_A... at 100%
2vwzRCSB PDB    PDBbind302aa, >2vwz_A... at 100%
2vx0RCSB PDB    PDBbind302aa, >2vx0_A... at 100%
2vx1RCSB PDB    PDBbind302aa, >2vx1_A... at 100%
2x9fRCSB PDB    PDBbind302aa, >2x9f_A... at 100%
4aw5RCSB PDB    PDBbind291aa, >4aw5_A... at 97%
4bb4RCSB PDB    PDBbind302aa, >4bb4_A... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID2xvd
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameEPHRIN TYPE-B RECEPTOR 4
Ligand NameAS6
EC.Number E.C.2.7.10.1
Resolution 1.7(Å)
Affinity (Kd/Ki/IC50)IC50=0.002uM
Release Year2011
Protein/NA SequenceCheck fasta file
Primary Reference(2011) Bioorg.Med.Chem.Lett. Vol. 21: pp. 2207
Ligand Properties
Formula C26H33N5O4S
Molecular Weight 511.636
Exact Mass 511.225
No. of atoms 69
No. of bonds 72
Polar Surface Area 116.27
LOGP Value 3.36      (Computed with XLOGP3)
5.03      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 9
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P54760  
Entrez Gene IDNCBI Entrez Gene ID: 2050  
ASDInformation of known allosteric effects of PDB entries

 
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