Related entries of code: 2zva
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2zv9RCSB PDB    PDBbind279aa, >2zv9_A... at 96%
3a4oRCSB PDB    PDBbind286aa, >3a4o_X... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
2y6oRCSB PDB    PDBbind1N1
3g5dRCSB PDB    PDBbind1N1
3k54RCSB PDB    PDBbind1N1
3octRCSB PDB    PDBbind1N1
5bvwRCSB PDB    PDBbind1N1

Entry Information
PDB ID2zva
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameTyrosine-protein kinase Lyn
Ligand Name1N1
EC.Number E.C.2.7.10.2
Resolution 2.6(Å)
Affinity (Kd/Ki/IC50)IC50=11nM
Release Year2008
Protein/NA SequenceCheck fasta file
Primary Reference(2009) J.Biol.Chem. Vol. 284: pp. 284-291
Ligand Properties
Formula C22H27ClN7O2S
Molecular Weight 489.013
Exact Mass 488.164
No. of atoms 60
No. of bonds 63
Polar Surface Area 135.95
LOGP Value 3.59      (Computed with XLOGP3)
3.68      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 9
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
ASDInformation of known allosteric effects of PDB entries

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