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Related entries of code: 2g01
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1ukhRCSB PDB    PDBbind11aa, >1UKH:B|PDBID|CHAIN|... *
2gmxRCSB PDB    PDBbind11aa, >2GMX:G|PDBID|CHAIN|... at 100%
2h96RCSB PDB    PDBbind11aa, >2H96:G|PDBID|CHAIN|... at 100%
2no3RCSB PDB    PDBbind11aa, >2NO3:G|PDBID|CHAIN|... at 100%
3ptgRCSB PDB    PDBbind11aa, >3PTG:J|PDBID|CHAIN|... at 100%
3v3vRCSB PDB    PDBbind11aa, >3V3V:B|PDBID|CHAIN|... at 100%
4hysRCSB PDB    PDBbind11aa, >4HYS:B|PDBID|CHAIN|... at 100%
4hyuRCSB PDB    PDBbind11aa, >4HYU:B|PDBID|CHAIN|... at 100%
4izyRCSB PDB    PDBbind11aa, >4IZY:B|PDBID|CHAIN|... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID2g01
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namemitogen-activated protein kinase 8
Ligand Name73Q
EC.Number E.C.
Resolution 3.5(Å)
Affinity (Kd/Ki/IC50)IC50=1.22uM
Release Year2006
Protein/NA SequenceCheck fasta file
Primary ReferenceBioorg.Med.Chem.Lett. v16 pp. 2590-4, 2006
Ligand Properties
Formula C12H10ClN3O2
Molecular Weight 263.680
Exact Mass 263.046
No. of atoms 28
No. of bonds 30
Polar Surface Area 60.05
LOGP Value 2.30      (Computed with XLOGP3)
2.09      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 1
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q9UQF2  P45983  
Entrez Gene IDNCBI Entrez Gene ID: 9479  5599  
ASDInformation of known allosteric effects of PDB entries

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