Display Options: Structure:  

Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 2gg9
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1xnzRCSB PDB    PDBbind264aa, >1XNZ:A|PDBID|CHAIN|... at 100%
1yvmRCSB PDB    PDBbind264aa, >1YVM:A|PDBID|CHAIN|... at 99%
2bb7RCSB PDB    PDBbind264aa, >2BB7:A|PDBID|CHAIN|... at 100%
2evcRCSB PDB    PDBbind264aa, >2EVC:A|PDBID|CHAIN|... at 100%
2evmRCSB PDB    PDBbind264aa, >2EVM:A|PDBID|CHAIN|... at 100%
2evoRCSB PDB    PDBbind264aa, >2EVO:B|PDBID|CHAIN|... at 100%
2gg0RCSB PDB    PDBbind263aa, >2GG0:A|PDBID|CHAIN|... at 100%
2gg2RCSB PDB    PDBbind263aa, >2GG2:A|PDBID|CHAIN|... at 100%
2gg3RCSB PDB    PDBbind263aa, >2GG3:A|PDBID|CHAIN|... at 100%
2gg5RCSB PDB    PDBbind263aa, >2GG5:A|PDBID|CHAIN|... at 100%
2gg7RCSB PDB    PDBbind263aa, >2GG7:A|PDBID|CHAIN|... at 100%
2gg8RCSB PDB    PDBbind263aa, >2GG8:A|PDBID|CHAIN|... at 100%
2ggbRCSB PDB    PDBbind263aa, >2GGB:A|PDBID|CHAIN|... at 100%
2p98RCSB PDB    PDBbind262aa, >2P98:A|PDBID|CHAIN|... at 100%
2p99RCSB PDB    PDBbind261aa, >2P99:A|PDBID|CHAIN|... at 100%
2p9aRCSB PDB    PDBbind262aa, >2P9A:A|PDBID|CHAIN|... at 100%
2q92RCSB PDB    PDBbind262aa, >2Q92:A|PDBID|CHAIN|... at 100%
2q93RCSB PDB    PDBbind263aa, >2Q93:A|PDBID|CHAIN|... at 100%
2q94RCSB PDB    PDBbind262aa, >2Q94:A|PDBID|CHAIN|... at 100%
2q95RCSB PDB    PDBbind263aa, >2Q95:A|PDBID|CHAIN|... at 100%
2q96RCSB PDB    PDBbind263aa, >2Q96:A|PDBID|CHAIN|... at 100%
3d27RCSB PDB    PDBbind261aa, >3D27:A|PDBID|CHAIN|... at 100%
4a6vRCSB PDB    PDBbind265aa, >4A6V:B|PDBID|CHAIN|... at 100%
4a6wRCSB PDB    PDBbind264aa, >4A6W:A|PDBID|CHAIN|... at 99%
4pncRCSB PDB    PDBbind264aa, >4PNC:A|PDBID|CHAIN|... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID2gg9
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMethionine aminopeptidase
Ligand NameU16
EC.Number E.C.
Resolution 1.05(Å)
Affinity (Kd/Ki/IC50)IC50=3.5uM
Release Year2006
Protein/NA SequenceCheck fasta file
Primary ReferenceProteins: Structures, Function and Bioinformatics. 2007, 66, 538-546.
Ligand Properties
Formula C22H36N3O5
Molecular Weight 422.538
Exact Mass 422.265
No. of atoms 66
No. of bonds 66
Polar Surface Area 132.37
LOGP Value 2.03      (Computed with XLOGP3)
1.44      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 14
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 1
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P0AE18  
Entrez Gene IDNCBI Entrez Gene ID: 947882  
ASDInformation of known allosteric effects of PDB entries

This site has been visited times since Nov 2007.

Address: 826 Zhangheng Road, Shanghai 201203, People's Republic of China      ICP NO: Shanghai-05005485-2
Group Leader: wangrx@fudan.edu.cn      Tel: +86-21-54925128      Webmaster: liuhai@mail.sioc.ac.cn
Copyright ©2007-2020    Department of Medicinal Chemistry, School of Pharmacy, Fudan University, P.R. China