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Related entries of code: 2wgj
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1r0pRCSB PDB    PDBbind312aa, >1R0P:A|PDBID|CHAIN|... at 100%
2rfnRCSB PDB    PDBbind310aa, >2RFN:B|PDBID|CHAIN|... at 96%
2wd1RCSB PDB    PDBbind292aa, >2WD1:A|PDBID|CHAIN|... at 98%
3a4pRCSB PDB    PDBbind319aa, >3A4P:A|PDBID|CHAIN|... at 98%
3c1xRCSB PDB    PDBbind373aa, >3C1X:A|PDBID|CHAIN|... *
3ccnRCSB PDB    PDBbind310aa, >3CCN:A|PDBID|CHAIN|... at 96%
3cd8RCSB PDB    PDBbind310aa, >3CD8:A|PDBID|CHAIN|... at 96%
3ce3RCSB PDB    PDBbind314aa, >3CE3:A|PDBID|CHAIN|... at 100%
3cthRCSB PDB    PDBbind314aa, >3CTH:A|PDBID|CHAIN|... at 100%
3ctjRCSB PDB    PDBbind314aa, >3CTJ:A|PDBID|CHAIN|... at 100%
3dkfRCSB PDB    PDBbind317aa, >3DKF:A|PDBID|CHAIN|... at 98%
3dkgRCSB PDB    PDBbind317aa, >3DKG:A|PDBID|CHAIN|... at 98%
3efjRCSB PDB    PDBbind310aa, >3EFJ:B|PDBID|CHAIN|... at 96%
3efkRCSB PDB    PDBbind310aa, >3EFK:B|PDBID|CHAIN|... at 96%
3f66RCSB PDB    PDBbind298aa, >3F66:B|PDBID|CHAIN|... at 98%
3f82RCSB PDB    PDBbind314aa, >3F82:A|PDBID|CHAIN|... at 100%
3i5nRCSB PDB    PDBbind309aa, >3I5N:A|PDBID|CHAIN|... at 97%
3l8vRCSB PDB    PDBbind314aa, >3L8V:A|PDBID|CHAIN|... at 100%
3lq8RCSB PDB    PDBbind302aa, >3LQ8:A|PDBID|CHAIN|... at 97%
3q6wRCSB PDB    PDBbind307aa, >3Q6W:A|PDBID|CHAIN|... at 97%
3qtiRCSB PDB    PDBbind314aa, >3QTI:B|PDBID|CHAIN|... at 99%
3r7oRCSB PDB    PDBbind307aa, >3R7O:A|PDBID|CHAIN|... at 97%
3rhkRCSB PDB    PDBbind318aa, >3RHK:B|PDBID|CHAIN|... at 92%
3u6hRCSB PDB    PDBbind309aa, >3U6H:A|PDBID|CHAIN|... at 97%
3u6iRCSB PDB    PDBbind309aa, >3U6I:A|PDBID|CHAIN|... at 97%
3zbxRCSB PDB    PDBbind306aa, >3ZBX:A|PDBID|CHAIN|... at 96%
3zc5RCSB PDB    PDBbind306aa, >3ZC5:A|PDBID|CHAIN|... at 96%
3zclRCSB PDB    PDBbind306aa, >3ZCL:A|PDBID|CHAIN|... at 96%
3zxzRCSB PDB    PDBbind306aa, >3ZXZ:A|PDBID|CHAIN|... at 96%
3zzeRCSB PDB    PDBbind306aa, >3ZZE:A|PDBID|CHAIN|... at 96%
4aoiRCSB PDB    PDBbind306aa, >4AOI:A|PDBID|CHAIN|... at 96%
4ap7RCSB PDB    PDBbind306aa, >4AP7:A|PDBID|CHAIN|... at 96%
4degRCSB PDB    PDBbind309aa, >4DEG:A|PDBID|CHAIN|... at 97%
4dehRCSB PDB    PDBbind309aa, >4DEH:A|PDBID|CHAIN|... at 97%
4deiRCSB PDB    PDBbind309aa, >4DEI:A|PDBID|CHAIN|... at 97%
4eevRCSB PDB    PDBbind317aa, >4EEV:A|PDBID|CHAIN|... at 93%
4knbRCSB PDB    PDBbind287aa, >4KNB:D|PDBID|CHAIN|... at 98%
4gg5RCSB PDB    PDBbind319aa, >4GG5:A|PDBID|CHAIN|... at 92%
4gg7RCSB PDB    PDBbind319aa, >4GG7:A|PDBID|CHAIN|... at 92%
4iwdRCSB PDB    PDBbind306aa, >4IWD:A|PDBID|CHAIN|... at 97%
4mxcRCSB PDB    PDBbind319aa, >4MXC:A|PDBID|CHAIN|... at 92%
4r1vRCSB PDB    PDBbind291aa, >4R1V:A|PDBID|CHAIN|... at 98%
4r1yRCSB PDB    PDBbind292aa, >4R1Y:A|PDBID|CHAIN|... at 98%
4xmoRCSB PDB    PDBbind309aa, >4XMO:A|PDBID|CHAIN|... at 97%
4xyfRCSB PDB    PDBbind309aa, >4XYF:A|PDBID|CHAIN|... at 97%
5eobRCSB PDB    PDBbind319aa, >5EOB:A|PDBID|CHAIN|... at 92%
5eycRCSB PDB    PDBbind309aa, >5EYC:A|PDBID|CHAIN|... at 97%
5eydRCSB PDB    PDBbind309aa, >5EYD:A|PDBID|CHAIN|... at 97%
5hlwRCSB PDB    PDBbind299aa, >5HLW:A|PDBID|CHAIN|... at 98%
5ho6RCSB PDB    PDBbind312aa, >5HO6:A|PDBID|CHAIN|... at 100%
5hoaRCSB PDB    PDBbind312aa, >5HOA:A|PDBID|CHAIN|... at 99%
5horRCSB PDB    PDBbind312aa, >5HOR:A|PDBID|CHAIN|... at 99%
5ya5RCSB PDB    PDBbind319aa, >5YA5:A|PDBID|CHAIN|... at 92%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
2xp2RCSB PDB    PDBbindVGH
2yfxRCSB PDB    PDBbindVGH
3zbfRCSB PDB    PDBbindVGH
4anqRCSB PDB    PDBbindVGH
4c9wRCSB PDB    PDBbindVGH
5aaaRCSB PDB    PDBbindVGH
5aabRCSB PDB    PDBbindVGH
5aacRCSB PDB    PDBbindVGH

Entry Information
PDB ID2wgj
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameHEPATOCYTE GROWTH FACTOR RECEPTOR
Ligand NameVGH
EC.Number E.C.2.7.10.1
Resolution 2(Å)
Affinity (Kd/Ki/IC50)Ki=0.002uM
Release Year2009
Protein/NA SequenceCheck fasta file
Primary Reference(2011) J.Med.Chem Vol. 54: pp. 6342
Ligand Properties
Formula C21H23Cl2FN5O
Molecular Weight 451.345
Exact Mass 450.126
No. of atoms 53
No. of bonds 56
Polar Surface Area 82.57
LOGP Value 3.69      (Computed with XLOGP3)
6.16      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 5
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P08581  
Entrez Gene IDNCBI Entrez Gene ID: 4233  
ASDInformation of known allosteric effects of PDB entries

 
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