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Related entries of code: 3lcd
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2i0vRCSB PDB    PDBbind335aa, >2I0V:A|PDBID|CHAIN|... at 91%
2i0yRCSB PDB    PDBbind335aa, >2I0Y:A|PDBID|CHAIN|... at 91%
2i1mRCSB PDB    PDBbind333aa, >2I1M:A|PDBID|CHAIN|... at 90%
3beaRCSB PDB    PDBbind333aa, >3BEA:A|PDBID|CHAIN|... at 91%
3dpkRCSB PDB    PDBbind335aa, >3DPK:A|PDBID|CHAIN|... at 91%
3krjRCSB PDB    PDBbind335aa, >3KRJ:A|PDBID|CHAIN|... at 91%
3krlRCSB PDB    PDBbind335aa, >3KRL:A|PDBID|CHAIN|... at 91%
3lcoRCSB PDB    PDBbind324aa, >3LCO:A|PDBID|CHAIN|... at 98%
4hw7RCSB PDB    PDBbind343aa, >4HW7:A|PDBID|CHAIN|... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID3lcd
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameKinase Domain of CSF-1R, Macrophage colony-stimulating factor 1 receptor
Ligand NameBDY
EC.Number E.C.2.7.10.1
Resolution 2.5(Å)
Affinity (Kd/Ki/IC50)IC50=40nM
Release Year2010
Protein/NA SequenceCheck fasta file
Primary Reference(2010) Bioorg.Med.Chem.Lett. Vol. 20: pp. 1543-1547
Ligand Properties
Formula C27H31Cl2N6O
Molecular Weight 526.481
Exact Mass 525.194
No. of atoms 67
No. of bonds 71
Polar Surface Area 88.58
LOGP Value 4.70      (Computed with XLOGP3)
6.09      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P07333  
Entrez Gene IDNCBI Entrez Gene ID: 1436  
ASDInformation of known allosteric effects of PDB entries

 
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