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Related entries of code: 3tt0
Entries with 90% protein sequence similarity cutoff in PDBbind
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Complexes with the same small molecule ligand
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No complexes with the same small molecule ligand are found!

Entry Information
PDB ID3tt0
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameBasic fibroblast growth factor receptor 1
Ligand Name07J
EC.Number E.C.2.7.10.1
Resolution 2.8(Å)
Affinity (Kd/Ki/IC50)IC50=0.9nM
Release Year2012
Protein/NA SequenceCheck fasta file
Primary Reference(2011) J.Med.Chem. Vol. 54: pp. 7066-7083
Ligand Properties
Formula C26H32Cl2N7O3
Molecular Weight 561.483
Exact Mass 560.194
No. of atoms 70
No. of bonds 73
Polar Surface Area 96.29
LOGP Value 4.66      (Computed with XLOGP3)
5.72      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 10
No. of Nitrogen and Oxygen Atoms: 10
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P11362  
Entrez Gene IDNCBI Entrez Gene ID: 2260  
ASDInformation of known allosteric effects of PDB entries

 
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