Related entries of code: 4an2
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3ornRCSB PDB    PDBbind307aa, >3orn_A... *
3os3RCSB PDB    PDBbind307aa, >3os3_A... at 100%
4an3RCSB PDB    PDBbind301aa, >4an3_A... at 96%
4an9RCSB PDB    PDBbind301aa, >4an9_A... at 96%
4anbRCSB PDB    PDBbind301aa, >4anb_A... at 96%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
4lmnRCSB PDB    PDBbindEUI

Entry Information
PDB ID4an2
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameDUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1, human MEK1
Ligand NameEUI
EC.Number E.C.2.7.12.2
Resolution 2.5(Å)
Affinity (Kd/Ki/IC50)IC50=0.9nM
Release Year2012
Protein/NA SequenceCheck fasta file
Primary Reference(2012) Acs Med.Chem.Lett. Vol. 3: pp. 416-421

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
ASDInformation of known allosteric effects of PDB entries

Display Options: Structure:     Draw Style:

Color Style:     PDB code:

           
Hold mouse button: left to rotate,middle to zoom,right to shift
 
This site has been visited times since Nov 2007.


Address: LingLing Road 345, Shanghai, 200032, China      ICP NO: Shanghai-05005485-2
Group Leader: wangrx@mail.sioc.ac.cn      Tel: +86-21-54925128      Webmaster: liuhai@mail.sioc.ac.cn
Copyright ©2007-2013    Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences