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Related entries of code: 4mbi
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1xwsRCSB PDB    PDBbind313aa, >1XWS:A|PDBID|CHAIN|... at 100%
1yhsRCSB PDB    PDBbind273aa, >1YHS:A|PDBID|CHAIN|... at 100%
1yi3RCSB PDB    PDBbind273aa, >1YI3:A|PDBID|CHAIN|... at 100%
2c3iRCSB PDB    PDBbind313aa, >2C3I:B|PDBID|CHAIN|... at 99%
2j2iRCSB PDB    PDBbind312aa, >2J2I:B|PDBID|CHAIN|... at 99%
2o3pRCSB PDB    PDBbind293aa, >2O3P:A|PDBID|CHAIN|... at 97%
2o63RCSB PDB    PDBbind293aa, >2O63:A|PDBID|CHAIN|... at 97%
2o64RCSB PDB    PDBbind293aa, >2O64:A|PDBID|CHAIN|... at 97%
2o65RCSB PDB    PDBbind293aa, >2O65:A|PDBID|CHAIN|... at 97%
2objRCSB PDB    PDBbind333aa, >2OBJ:A|PDBID|CHAIN|... at 96%
2xixRCSB PDB    PDBbind301aa, >2XIX:A|PDBID|CHAIN|... at 99%
2xiyRCSB PDB    PDBbind301aa, >2XIY:A|PDBID|CHAIN|... at 99%
2xizRCSB PDB    PDBbind301aa, >2XIZ:A|PDBID|CHAIN|... at 99%
2xj0RCSB PDB    PDBbind301aa, >2XJ0:A|PDBID|CHAIN|... at 99%
2xj1RCSB PDB    PDBbind301aa, >2XJ1:A|PDBID|CHAIN|... at 99%
2xj2RCSB PDB    PDBbind301aa, >2XJ2:A|PDBID|CHAIN|... at 99%
3bgpRCSB PDB    PDBbind333aa, >3BGP:A|PDBID|CHAIN|... at 96%
3bgqRCSB PDB    PDBbind333aa, >3BGQ:A|PDBID|CHAIN|... at 96%
3bgzRCSB PDB    PDBbind333aa, >3BGZ:A|PDBID|CHAIN|... at 96%
3bwfRCSB PDB    PDBbind313aa, >3BWF:A|PDBID|CHAIN|... at 99%
3c4eRCSB PDB    PDBbind273aa, >3C4E:D|PDBID|CHAIN|... at 100%
3dcvRCSB PDB    PDBbind328aa, >3DCV:A|PDBID|CHAIN|... at 96%
3f2aRCSB PDB    PDBbind300aa, >3F2A:A|PDBID|CHAIN|... at 100%
3ma3RCSB PDB    PDBbind313aa, >3MA3:A|PDBID|CHAIN|... at 99%
3jxwRCSB PDB    PDBbind294aa, >3JXW:A|PDBID|CHAIN|... at 96%
3jy0RCSB PDB    PDBbind294aa, >3JY0:A|PDBID|CHAIN|... at 96%
3jyaRCSB PDB    PDBbind294aa, >3JYA:A|PDBID|CHAIN|... at 96%
3r00RCSB PDB    PDBbind299aa, >3R00:A|PDBID|CHAIN|... at 95%
3r01RCSB PDB    PDBbind299aa, >3R01:A|PDBID|CHAIN|... at 95%
3r02RCSB PDB    PDBbind299aa, >3R02:A|PDBID|CHAIN|... at 95%
3r04RCSB PDB    PDBbind299aa, >3R04:A|PDBID|CHAIN|... at 95%
3uixRCSB PDB    PDBbind298aa, >3UIX:A|PDBID|CHAIN|... at 95%
3umwRCSB PDB    PDBbind298aa, >3UMW:A|PDBID|CHAIN|... at 95%
3umxRCSB PDB    PDBbind298aa, >3UMX:A|PDBID|CHAIN|... at 95%
3vbqRCSB PDB    PDBbind299aa, >3VBQ:A|PDBID|CHAIN|... at 95%
3vbtRCSB PDB    PDBbind299aa, >3VBT:A|PDBID|CHAIN|... at 95%
3vbvRCSB PDB    PDBbind299aa, >3VBV:A|PDBID|CHAIN|... at 95%
3vbwRCSB PDB    PDBbind299aa, >3VBW:A|PDBID|CHAIN|... at 95%
3vbxRCSB PDB    PDBbind299aa, >3VBX:A|PDBID|CHAIN|... at 95%
3vbyRCSB PDB    PDBbind299aa, >3VBY:A|PDBID|CHAIN|... at 95%
3vc4RCSB PDB    PDBbind299aa, >3VC4:A|PDBID|CHAIN|... at 95%
4a7cRCSB PDB    PDBbind308aa, >4A7C:A|PDBID|CHAIN|... at 92%
4aluRCSB PDB    PDBbind328aa, >4ALU:A|PDBID|CHAIN|... at 95%
4alvRCSB PDB    PDBbind328aa, >4ALV:A|PDBID|CHAIN|... at 95%
4alwRCSB PDB    PDBbind328aa, >4ALW:A|PDBID|CHAIN|... at 95%
4bznRCSB PDB    PDBbind314aa, >4BZN:A|PDBID|CHAIN|... at 99%
4bzoRCSB PDB    PDBbind314aa, >4BZO:A|PDBID|CHAIN|... at 99%
4dtkRCSB PDB    PDBbind276aa, >4DTK:A|PDBID|CHAIN|... at 100%
4enxRCSB PDB    PDBbind298aa, >4ENX:A|PDBID|CHAIN|... at 95%
4enyRCSB PDB    PDBbind298aa, >4ENY:A|PDBID|CHAIN|... at 95%
4k0yRCSB PDB    PDBbind274aa, >4K0Y:A|PDBID|CHAIN|... at 100%
4k18RCSB PDB    PDBbind277aa, >4K18:A|PDBID|CHAIN|... at 100%
4k1bRCSB PDB    PDBbind273aa, >4K1B:A|PDBID|CHAIN|... at 100%
4lm5RCSB PDB    PDBbind298aa, >4LM5:A|PDBID|CHAIN|... at 95%
4lmuRCSB PDB    PDBbind298aa, >4LMU:A|PDBID|CHAIN|... at 95%
4mblRCSB PDB    PDBbind293aa, >4MBL:A|PDBID|CHAIN|... at 97%
4n6yRCSB PDB    PDBbind328aa, >4N6Y:A|PDBID|CHAIN|... at 96%
4n6zRCSB PDB    PDBbind328aa, >4N6Z:A|PDBID|CHAIN|... at 96%
4n70RCSB PDB    PDBbind328aa, >4N70:A|PDBID|CHAIN|... at 96%
4rpvRCSB PDB    PDBbind410aa, >4RPV:A|PDBID|CHAIN|... *
4ty1RCSB PDB    PDBbind286aa, >4TY1:A|PDBID|CHAIN|... at 95%
4wrsRCSB PDB    PDBbind286aa, >4WRS:A|PDBID|CHAIN|... at 95%
4wsyRCSB PDB    PDBbind286aa, >4WSY:A|PDBID|CHAIN|... at 95%
4wt6RCSB PDB    PDBbind286aa, >4WT6:A|PDBID|CHAIN|... at 95%
4xh6RCSB PDB    PDBbind294aa, >4XH6:A|PDBID|CHAIN|... at 96%
4xhkRCSB PDB    PDBbind315aa, >4XHK:B|PDBID|CHAIN|... at 99%
5dgzRCSB PDB    PDBbind299aa, >5DGZ:A|PDBID|CHAIN|... at 95%
5dhjRCSB PDB    PDBbind299aa, >5DHJ:A|PDBID|CHAIN|... at 95%
5diaRCSB PDB    PDBbind299aa, >5DIA:A|PDBID|CHAIN|... at 95%
5dwrRCSB PDB    PDBbind328aa, >5DWR:A|PDBID|CHAIN|... at 96%
5eolRCSB PDB    PDBbind286aa, >5EOL:A|PDBID|CHAIN|... at 95%
5iisRCSB PDB    PDBbind277aa, >5IIS:A|PDBID|CHAIN|... at 100%
5ipjRCSB PDB    PDBbind286aa, >5IPJ:A|PDBID|CHAIN|... at 95%
5kziRCSB PDB    PDBbind286aa, >5KZI:A|PDBID|CHAIN|... at 95%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID4mbi
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameSerine/threonine-protein kinase pim-1
Ligand Name26K
EC.Number E.C.2.7.11.1
Resolution 2.3(Å)
Affinity (Kd/Ki/IC50)IC50=7nM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference(2013) Bioorg.Med.Chem.Lett. Vol. 23: pp. 6178-6182
Ligand Properties
Formula C13H19N7
Molecular Weight 273.337
Exact Mass 273.170
No. of atoms 39
No. of bonds 41
Polar Surface Area 77.93
LOGP Value 1.29      (Computed with XLOGP3)
-0.83      (Computed with Open Babel)
Drug likenessNo. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 5
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P11309  
Entrez Gene IDNCBI Entrez Gene ID: 5292  
ASDInformation of known allosteric effects of PDB entries

 
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