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Related entries of code: 1onp
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1t1rRCSB PDB    PDBbind398aa, >1T1R:B|PDBID|CHAIN|... at 99%
1t1sRCSB PDB    PDBbind398aa, >1T1S:B|PDBID|CHAIN|... at 99%
3r0iRCSB PDB    PDBbind410aa, >3R0I:B|PDBID|CHAIN|... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3upyRCSB PDB    PDBbindFOM

Entry Information
PDB ID1onp
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameE. coli 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR)
Ligand NameFOM
EC.Number E.C.
Resolution 2.5(Å)
Affinity (Kd/Ki/IC50)IC50=0.030uM
Release Year2003
Protein/NA SequenceCheck fasta file
Primary Reference (2011) ACS Med. Chem. Lett., Vol.2, pp.165-170
Ligand Properties
Formula C4H10NO5P
Molecular Weight 183.100
Exact Mass 183.030
No. of atoms 21
No. of bonds 20
Polar Surface Area 120.78
LOGP Value -2.25      (Computed with XLOGP3)
0.21      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 0
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 4
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 0
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P45568  
Entrez Gene IDNCBI Entrez Gene ID: 945019  
ASDInformation of known allosteric effects of PDB entries

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