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Related entries of code: 2ivu
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2x2kRCSB PDB    PDBbind314aa, >2X2K_1|Chain... at 100%
2x2lRCSB PDB    PDBbind314aa, >2X2L_1|Chain... at 100%
2x2mRCSB PDB    PDBbind314aa, >2X2M_1|Chains... at 100%
4ckiRCSB PDB    PDBbind314aa, >4CKI_1|Chain... at 99%
4ckjRCSB PDB    PDBbind314aa, >4CKJ_1|Chain... at 100%
5amnRCSB PDB    PDBbind299aa, >5AMN_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID2ivu
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Nameproto-oncogene tyrosine-protein kinase
Ligand NameZD6
EC.Number E.C.2.7.10.1
Resolution 2.5(Å)
Affinity (Kd/Ki/IC50)Ki=375nM
Release Year2006
Protein/NA SequenceCheck fasta file
Primary Reference J.Biol.Chem.v281;pp.33577
Ligand Properties
Formula C22H25BrFN4O2
Molecular Weight 476.362
Exact Mass 475.114
No. of atoms 55
No. of bonds 58
Polar Surface Area 60.71
LOGP Value 4.93      (Computed with XLOGP3)
5.23      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P07949  
Entrez Gene IDNCBI Entrez Gene ID: 5979  
ASDInformation of known allosteric effects of PDB entries

 
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