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Related entries of code: 2lzg
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4odeRCSB PDB    PDBbind105aa, >4ODE:A|PDBID|CHAIN|... at 100%
4odfRCSB PDB    PDBbind105aa, >4ODF:A|PDBID|CHAIN|... at 100%
4ognRCSB PDB    PDBbind105aa, >4OGN:A|PDBID|CHAIN|... at 100%
4ogtRCSB PDB    PDBbind105aa, >4OGT:A|PDBID|CHAIN|... at 100%
4wt2RCSB PDB    PDBbind105aa, >4WT2:A|PDBID|CHAIN|... at 100%
5j7fRCSB PDB    PDBbind125aa, >5J7F:D|PDBID|CHAIN|... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID2lzg
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameE3 ubiquitin-protein ligase Mdm2
Ligand Name13Q
EC.Number E.C.6.3.2
Resolution NMR
Affinity (Kd/Ki/IC50)Kd=16.9nM
Release Year2012
Protein/NA SequenceCheck fasta file
Primary Reference (2012) J.Am.Chem.Soc. Vol. 134: pp. 17059-17067
Ligand Properties
Formula C23H23Cl2NO3
Molecular Weight 432.340
Exact Mass 431.105
No. of atoms 52
No. of bonds 55
Polar Surface Area 57.61
LOGP Value 5.48      (Computed with XLOGP3)
5.49      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 0
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 4
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q00987  
Entrez Gene IDNCBI Entrez Gene ID: 4193  
ASDInformation of known allosteric effects of PDB entries

 
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