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Related entries of code: 2osc
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2oo8RCSB PDB    PDBbind317aa, >2OO8_1|Chain... at 99%
2p4iRCSB PDB    PDBbind317aa, >2P4I_1|Chains... at 99%
2wqbRCSB PDB    PDBbind324aa, >2WQB_1|Chain... *
6mweRCSB PDB    PDBbind317aa, >6MWE_1|Chains... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID2osc
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameAngiopoietin-1 receptor
Ligand NameMUH
EC.Number E.C.2.7.10.1
Resolution 2.8(Å)
Affinity (Kd/Ki/IC50)IC50=17nM
Release Year2007
Protein/NA SequenceCheck fasta file
Primary Reference Bioorg.Med.Chem.Lett. 17: 2886-2889
Ligand Properties
Formula C24H18F3N5O
Molecular Weight 449.428
Exact Mass 449.146
No. of atoms 51
No. of bonds 54
Polar Surface Area 79.8
LOGP Value 4.75      (Computed with XLOGP3)
6.01      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q02763  
Entrez Gene IDNCBI Entrez Gene ID: 7010  
ASDInformation of known allosteric effects of PDB entries

 
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