Browse entries in the PDBbind-CN Database

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Related entries of code: 2xas
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2xafRCSB PDB    PDBbind482aa, >2XAF_2|Chain... *
2xagRCSB PDB    PDBbind482aa, >2XAG_2|Chain... at 100%
2xahRCSB PDB    PDBbind482aa, >2XAH_2|Chain... at 100%
2xajRCSB PDB    PDBbind482aa, >2XAJ_2|Chain... at 100%
2xaqRCSB PDB    PDBbind482aa, >2XAQ_2|Chain... at 100%
3zmtRCSB PDB    PDBbind482aa, >3ZMT_2|Chain... at 100%
3zmuRCSB PDB    PDBbind482aa, >3ZMU_2|Chain... at 100%
3zmvRCSB PDB    PDBbind482aa, >3ZMV_2|Chain... at 100%
3zmzRCSB PDB    PDBbind482aa, >3ZMZ_2|Chain... at 100%
3zn0RCSB PDB    PDBbind482aa, >3ZN0_2|Chain... at 100%
3zn1RCSB PDB    PDBbind482aa, >3ZN1_2|Chain... at 100%
4uv8RCSB PDB    PDBbind482aa, >4UV8_2|Chain... at 100%
4uv9RCSB PDB    PDBbind482aa, >4UV9_2|Chain... at 100%
4uvaRCSB PDB    PDBbind482aa, >4UVA_2|Chain... at 100%
4uvbRCSB PDB    PDBbind482aa, >4UVB_2|Chain... at 100%
4uvcRCSB PDB    PDBbind482aa, >4UVC_2|Chain... at 100%
5l3eRCSB PDB    PDBbind178aa, >5L3E_2|Chain... at 100%
5lbqRCSB PDB    PDBbind178aa, >5LBQ_2|Chain... at 100%
5lgnRCSB PDB    PDBbind133aa, >5LGN_2|Chain... at 100%
5lgtRCSB PDB    PDBbind178aa, >5LGT_2|Chain... at 100%
5lguRCSB PDB    PDBbind178aa, >5LGU_2|Chain... at 100%
5lhgRCSB PDB    PDBbind482aa, >5LHG_2|Chain... at 100%
5lhhRCSB PDB    PDBbind482aa, >5LHH_2|Chain... at 100%
5lhiRCSB PDB    PDBbind482aa, >5LHI_2|Chain... at 100%
5yjbRCSB PDB    PDBbind140aa, >5YJB_2|Chain... at 95%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID2xas
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameLYSINE-SPECIFIC HISTONE DEMETHYLASE 1 and REST COREPRESSOR 1
Ligand NameM80
EC.Number E.C.-.-.-.-
Resolution 3.2(Å)
Affinity (Kd/Ki/IC50)Ki=1.3uM
Release Year2010
Protein/NA SequenceCheck fasta file
Primary Reference (2010) J.Am.Chem.Soc. Vol. 132: pp. 6827-6
Ligand Properties
Formula C53H61N11O19P2
Molecular Weight 1218.060
Exact Mass 1217.360
No. of atoms 146
No. of bonds 154
Polar Surface Area 476.39
LOGP Value -0.04      (Computed with XLOGP3)
3.27      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 10
No. of Hydrogen Bond Acceptors: 19
No. of Rotatable Bonds: 34
No. of Nitrogen and Oxygen Atoms: 30
No. of Rings: 9
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): O60341  Q9UKL0  
Entrez Gene IDNCBI Entrez Gene ID: 23028  23186  
ASDInformation of known allosteric effects of PDB entries

 
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