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Related entries of code: 3lbj
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2n06RCSB PDB    PDBbind89aa, >2N06:A|PDBID|CHAIN|... at 100%
2n0uRCSB PDB    PDBbind89aa, >2N0U:A|PDBID|CHAIN|... at 100%
2n0wRCSB PDB    PDBbind89aa, >2N0W:A|PDBID|CHAIN|... at 100%
2n14RCSB PDB    PDBbind89aa, >2N14:A|PDBID|CHAIN|... at 100%
2vyrRCSB PDB    PDBbind101aa, >2VYR:D|PDBID|CHAIN|... at 100%
3fe7RCSB PDB    PDBbind100aa, >3FE7:A|PDBID|CHAIN|... at 95%
3feaRCSB PDB    PDBbind100aa, >3FEA:A|PDBID|CHAIN|... at 95%
3u15RCSB PDB    PDBbind100aa, >3U15:D|PDBID|CHAIN|... at 95%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID3lbj
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namehuman MDMX protein
Ligand NameWW8
EC.Number E.C.-.-.-.-
Resolution 1.5(Å)
Affinity (Kd/Ki/IC50)Ki=11uM
Release Year2010
Protein/NA SequenceCheck fasta file
Primary Reference (2010) Cell Cycle Vol. 9:5, pp. 1104-1111
Ligand Properties
Formula C35H40Cl2N6O
Molecular Weight 631.638
Exact Mass 630.264
No. of atoms 84
No. of bonds 89
Polar Surface Area 62.8
LOGP Value 7.29      (Computed with XLOGP3)
4.26      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 11
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 6
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): O15151  
Entrez Gene IDNCBI Entrez Gene ID: 4194  
ASDInformation of known allosteric effects of PDB entries

 
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