Browse entries in the PDBbind-CN Database

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Related entries of code: 3n7o
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1t31RCSB PDB    PDBbind226aa, >1T31_1|Chain... *
2hvxRCSB PDB    PDBbind226aa, >2HVX_1|Chain... at 100%
3s0nRCSB PDB    PDBbind226aa, >3S0N_1|Chain... at 100%
4k2yRCSB PDB    PDBbind226aa, >4K2Y_1|Chain... at 100%
4k5zRCSB PDB    PDBbind226aa, >4K5Z_1|Chain... at 100%
4k60RCSB PDB    PDBbind226aa, >4K60_1|Chain... at 100%
4k69RCSB PDB    PDBbind226aa, >4K69_1|Chain... at 100%
4kp0RCSB PDB    PDBbind226aa, >4KP0_1|Chain... at 98%
5yjmRCSB PDB    PDBbind226aa, >5YJM_1|Chain... at 98%
5yjpRCSB PDB    PDBbind226aa, >5YJP_1|Chain... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID3n7o
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein Namehuman chymase
Ligand NameN7O
EC.Number E.C.3.4.21.39
Resolution 1.8(Å)
Affinity (Kd/Ki/IC50)Ki=72nM
Release Year2010
Protein/NA SequenceCheck fasta file
Primary Reference (2010) Biochem Pharmacol Vol. 80: pp. 1033-1041
Ligand Properties
Formula C19H16ClF2NO3PS
Molecular Weight 442.824
Exact Mass 442.025
No. of atoms 44
No. of bonds 46
Polar Surface Area 111.39
LOGP Value 3.68      (Computed with XLOGP3)
5.51      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 4
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P23946  
Entrez Gene IDNCBI Entrez Gene ID: 1215  
ASDInformation of known allosteric effects of PDB entries
 
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