Browse entries in the PDBbind-CN Database

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Related entries of code: 3pvu
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3ah8RCSB PDB    PDBbind78aa, >3AH8_3|Chain... *
3krwRCSB PDB    PDBbind74aa, >3KRW_3|Chain... at 90%
3krxRCSB PDB    PDBbind74aa, >3KRX_3|Chain... at 90%
3pvwRCSB PDB    PDBbind74aa, >3PVW_3|Chain... at 90%
4mk0RCSB PDB    PDBbind59aa, >4MK0_3|Chain... at 100%
4pnkRCSB PDB    PDBbind71aa, >4PNK_3|Chain... at 100%
5he0RCSB PDB    PDBbind71aa, >5HE0_3|Chain... at 98%
5he1RCSB PDB    PDBbind71aa, >5HE1_3|Chain... at 100%
5he2RCSB PDB    PDBbind71aa, >5HE2_3|Chain... at 100%
5he3RCSB PDB    PDBbind71aa, >5HE3_3|Chain... at 98%
5ukkRCSB PDB    PDBbind57aa, >5UKK_3|Chain... at 100%
5uklRCSB PDB    PDBbind62aa, >5UKL_3|Chain... at 98%
5ukmRCSB PDB    PDBbind71aa, >5UKM_3|Chain... at 98%
5wg3RCSB PDB    PDBbind71aa, >5WG3_3|Chain... at 100%
5wg4RCSB PDB    PDBbind71aa, >5WG4_3|Chain... at 100%
5wg5RCSB PDB    PDBbind71aa, >5WG5_3|Chain... at 100%
6c2yRCSB PDB    PDBbind77aa, >6C2Y_3|Chain... at 92%
6gdgRCSB PDB    PDBbind71aa, >6GDG_3|Chain... at 100%
6n4bRCSB PDB    PDBbind71aa, >6N4B_3|Chain... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
5uuuRCSB PDB    PDBbindQRW

Entry Information
PDB ID3pvu
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameGRK2-G beta gamma complex
Ligand NameQRW
EC.Number E.C.2.7.11.15
Resolution 2.48(Å)
Affinity (Kd/Ki/IC50)IC50=290nM
Release Year2011
Protein/NA SequenceCheck fasta file
Primary Reference (2011) Mol.Pharmacol. Vol. 80: pp. 294-303
Ligand Properties
Formula C24H21F3N6O
Molecular Weight 466.458
Exact Mass 466.173
No. of atoms 55
No. of bonds 58
Polar Surface Area 84.73
LOGP Value 3.19      (Computed with XLOGP3)
4.90      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P62871  P63212  P21146  
Entrez Gene IDNCBI Entrez Gene ID: 281201  281203  282682  
ASDInformation of known allosteric effects of PDB entries

 
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