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Related entries of code: 4gxs
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1ftjRCSB PDB    PDBbind263aa, >1FTJ:C|PDBID|CHAIN|... at 98%
1ftkRCSB PDB    PDBbind279aa, >1FTK:A|PDBID|CHAIN|... *
1ftlRCSB PDB    PDBbind263aa, >1FTL:B|PDBID|CHAIN|... at 98%
1ftmRCSB PDB    PDBbind263aa, >1FTM:C|PDBID|CHAIN|... at 98%
1fw0RCSB PDB    PDBbind263aa, >1FW0:A|PDBID|CHAIN|... at 98%
1m5bRCSB PDB    PDBbind263aa, >1M5B:C|PDBID|CHAIN|... at 98%
1m5cRCSB PDB    PDBbind263aa, >1M5C:A|PDBID|CHAIN|... at 98%
1m5dRCSB PDB    PDBbind263aa, >1M5D:A|PDBID|CHAIN|... at 98%
1m5eRCSB PDB    PDBbind263aa, >1M5E:C|PDBID|CHAIN|... at 98%
1m5fRCSB PDB    PDBbind263aa, >1M5F:C|PDBID|CHAIN|... at 98%
1mm6RCSB PDB    PDBbind263aa, >1MM6:B|PDBID|CHAIN|... at 98%
1mm7RCSB PDB    PDBbind263aa, >1MM7:C|PDBID|CHAIN|... at 98%
1mqdRCSB PDB    PDBbind261aa, >1MQD:D|PDBID|CHAIN|... at 98%
1mqgRCSB PDB    PDBbind263aa, >1MQG:B|PDBID|CHAIN|... at 98%
1mqhRCSB PDB    PDBbind263aa, >1MQH:A|PDBID|CHAIN|... at 98%
1mqiRCSB PDB    PDBbind263aa, >1MQI:A|PDBID|CHAIN|... at 98%
1mqjRCSB PDB    PDBbind263aa, >1MQJ:A|PDBID|CHAIN|... at 98%
1ms7RCSB PDB    PDBbind263aa, >1MS7:C|PDBID|CHAIN|... at 98%
1mxuRCSB PDB    PDBbind263aa, >1MXU:C|PDBID|CHAIN|... at 98%
1my2RCSB PDB    PDBbind263aa, >1MY2:C|PDBID|CHAIN|... at 98%
1my3RCSB PDB    PDBbind263aa, >1MY3:C|PDBID|CHAIN|... at 98%
1my4RCSB PDB    PDBbind263aa, >1MY4:C|PDBID|CHAIN|... at 98%
1n0tRCSB PDB    PDBbind263aa, >1N0T:D|PDBID|CHAIN|... at 98%
1nnkRCSB PDB    PDBbind263aa, >1NNK:A|PDBID|CHAIN|... at 98%
1p1nRCSB PDB    PDBbind263aa, >1P1N:A|PDBID|CHAIN|... at 98%
1p1oRCSB PDB    PDBbind263aa, >1P1O:A|PDBID|CHAIN|... at 98%
1p1qRCSB PDB    PDBbind263aa, >1P1Q:C|PDBID|CHAIN|... at 98%
1syhRCSB PDB    PDBbind263aa, >1SYH:A|PDBID|CHAIN|... at 98%
1syiRCSB PDB    PDBbind263aa, >1SYI:B|PDBID|CHAIN|... at 98%
1wvjRCSB PDB    PDBbind263aa, >1WVJ:A|PDBID|CHAIN|... at 98%
1xhyRCSB PDB    PDBbind263aa, >1XHY:A|PDBID|CHAIN|... at 98%
2al5RCSB PDB    PDBbind263aa, >2AL5:B|PDBID|CHAIN|... at 98%
2cmoRCSB PDB    PDBbind263aa, >2CMO:B|PDBID|CHAIN|... at 98%
2i3vRCSB PDB    PDBbind259aa, >2I3V:D|PDBID|CHAIN|... at 99%
2p2aRCSB PDB    PDBbind263aa, >2P2A:B|PDBID|CHAIN|... at 98%
3bftRCSB PDB    PDBbind263aa, >3BFT:C|PDBID|CHAIN|... at 98%
3bfuRCSB PDB    PDBbind263aa, >3BFU:D|PDBID|CHAIN|... at 98%
3bkiRCSB PDB    PDBbind263aa, >3BKI:P|PDBID|CHAIN|... at 98%
3h03RCSB PDB    PDBbind258aa, >3H03:G|PDBID|CHAIN|... at 99%
3h06RCSB PDB    PDBbind258aa, >3H06:P|PDBID|CHAIN|... at 99%
3pd8RCSB PDB    PDBbind261aa, >3PD8:C|PDBID|CHAIN|... at 99%
3pd9RCSB PDB    PDBbind260aa, >3PD9:B|PDBID|CHAIN|... at 99%
3rtfRCSB PDB    PDBbind258aa, >3RTF:F|PDBID|CHAIN|... at 99%
3tdjRCSB PDB    PDBbind263aa, >3TDJ:B|PDBID|CHAIN|... at 98%
3tzaRCSB PDB    PDBbind263aa, >3TZA:B|PDBID|CHAIN|... at 98%
3ua8RCSB PDB    PDBbind263aa, >3UA8:A|PDBID|CHAIN|... at 98%
4g8mRCSB PDB    PDBbind263aa, >4G8M:B|PDBID|CHAIN|... at 98%
4igtRCSB PDB    PDBbind263aa, >4IGT:A|PDBID|CHAIN|... at 98%
4isuRCSB PDB    PDBbind263aa, >4ISU:D|PDBID|CHAIN|... at 98%
4n07RCSB PDB    PDBbind263aa, >4N07:C|PDBID|CHAIN|... at 98%
4o3aRCSB PDB    PDBbind263aa, >4O3A:C|PDBID|CHAIN|... at 98%
4o3bRCSB PDB    PDBbind263aa, >4O3B:B|PDBID|CHAIN|... at 98%
4o3cRCSB PDB    PDBbind263aa, >4O3C:A|PDBID|CHAIN|... at 98%
4u4sRCSB PDB    PDBbind263aa, >4U4S:A|PDBID|CHAIN|... at 98%
4u4xRCSB PDB    PDBbind263aa, >4U4X:B|PDBID|CHAIN|... at 98%
4x48RCSB PDB    PDBbind275aa, >4X48:C|PDBID|CHAIN|... at 98%
5cbrRCSB PDB    PDBbind264aa, >5CBR:A|PDBID|CHAIN|... at 98%
5cbsRCSB PDB    PDBbind264aa, >5CBS:D|PDBID|CHAIN|... at 98%
5elvRCSB PDB    PDBbind264aa, >5ELV:B|PDBID|CHAIN|... at 97%
5fhmRCSB PDB    PDBbind264aa, >5FHM:B|PDBID|CHAIN|... at 98%
5fhnRCSB PDB    PDBbind264aa, >5FHN:A|PDBID|CHAIN|... at 98%
5fhoRCSB PDB    PDBbind264aa, >5FHO:D|PDBID|CHAIN|... at 98%
5ng9RCSB PDB    PDBbind264aa, >5NG9:A|PDBID|CHAIN|... at 98%
5nihRCSB PDB    PDBbind264aa, >5NIH:B|PDBID|CHAIN|... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID4gxs
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameGlutamate receptor 2
Ligand Name0YS
EC.Number E.C.-.-.-.-
Resolution 1.96(Å)
Affinity (Kd/Ki/IC50)IC50>100uM
Release Year2012
Protein/NA SequenceCheck fasta file
Primary Reference (2012) J.Biol.Chem. Vol. 287: pp. 41007-41013
Ligand Properties
Formula C18H23Cl2N3O9
Molecular Weight 496.296
Exact Mass 495.081
No. of atoms 55
No. of bonds 56
Polar Surface Area 225.71
LOGP Value -2.18      (Computed with XLOGP3)
-0.16      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 5
No. of Hydrogen Bond Acceptors: 9
No. of Rotatable Bonds: 12
No. of Nitrogen and Oxygen Atoms: 12
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P19491  
Entrez Gene IDNCBI Entrez Gene ID: 29627  
ASDInformation of known allosteric effects of PDB entries

 
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