Browse entries in the PDBbind-CN Database

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Related entries of code: 4b2d
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1t5aRCSB PDB    PDBbind567aa, >1T5A_1|Chains... *
4fxfRCSB PDB    PDBbind551aa, >4FXF_1|Chains... at 98%
4fxjRCSB PDB    PDBbind551aa, >4FXJ_1|Chains... at 98%
6b6uRCSB PDB    PDBbind525aa, >6B6U_1|Chains... at 99%
6gg4RCSB PDB    PDBbind551aa, >6GG4_1|Chains... at 97%
6gg5RCSB PDB    PDBbind551aa, >6GG5_1|Chains... at 97%
6nu5RCSB PDB    PDBbind551aa, >6NU5_1|Chains... at 97%
6nu1RCSB PDB    PDBbind551aa, >6NU1_1|Chains... at 97%
6gg3RCSB PDB    PDBbind551aa, >6GG3_1|Chains... at 97%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3atpRCSB PDB    PDBbindSER
3q1xRCSB PDB    PDBbindSER
4io4RCSB PDB    PDBbindSER
5aveRCSB PDB    PDBbindSER
6bmiRCSB PDB    PDBbindSER
6iouRCSB PDB    PDBbindSER

Entry Information
PDB ID4b2d
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NamePYRUVATE KINASE ISOZYMES M1/M2
Ligand NameSER
EC.Number E.C.2.7.1.40
Resolution 2.3(Å)
Affinity (Kd/Ki/IC50)Kd=0.20mM
Release Year2012
Protein/NA SequenceCheck fasta file
Primary Reference (2012) Nature Vol. 491: pp. 458
Ligand Properties
Formula C3H8NO3
Molecular Weight 106.101
Exact Mass 106.050
No. of atoms 15
No. of bonds 14
Polar Surface Area 85.17
LOGP Value -3.17      (Computed with XLOGP3)
-2.33      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 2
No. of Nitrogen and Oxygen Atoms: 4
No. of Rings: 0
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P14618  
Entrez Gene IDNCBI Entrez Gene ID: 5315  
ASDInformation of known allosteric effects of PDB entries

 
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