Browse entries in the PDBbind-CN Database

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Related entries of code: 4j3e
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1ttvRCSB PDB    PDBbind107aa, >1TTV_1|Chain... *
4ipfRCSB PDB    PDBbind85aa, >4IPF_1|Chain... at 100%
4j74RCSB PDB    PDBbind86aa, >4J74_1|Chain... at 98%
4j7dRCSB PDB    PDBbind86aa, >4J7D_1|Chain... at 98%
4j7eRCSB PDB    PDBbind86aa, >4J7E_1|Chain... at 98%
4jrgRCSB PDB    PDBbind85aa, >4JRG_1|Chains... at 100%
4jscRCSB PDB    PDBbind86aa, >4JSC_1|Chains... at 98%
4lwtRCSB PDB    PDBbind86aa, >4LWT_1|Chain... at 98%
4lwuRCSB PDB    PDBbind85aa, >4LWU_1|Chain... at 100%
4lwvRCSB PDB    PDBbind85aa, >4LWV_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
4hg7RCSB PDB    PDBbindNUT
Entry Information
PDB ID4j3e
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameE3 ubiquitin-protein ligase Mdm2 (I50L, P92H, L95I mutation)
Ligand NameNUT
EC.Number E.C.6.3.2
Resolution 1.91(Å)
Affinity (Kd/Ki/IC50)IC50=0.088uM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference (2013) ACS MED.CHEM.LETT. Vol. 4: pp. 466-469
Ligand Properties
Formula C30H30Cl2N4O4
Molecular Weight 581.490
Exact Mass 580.164
No. of atoms 70
No. of bonds 74
Polar Surface Area 83.47
LOGP Value 5.20      (Computed with XLOGP3)
5.53      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P56273  
Entrez Gene IDNo matched NCBI Entrez Gene ID found!
ASDInformation of known allosteric effects of PDB entries
 
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