Browse entries in the PDBbind-CN Database

Display Options: Structure:  




Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

           
Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 4lnb
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4lngRCSB PDB    PDBbind367aa, >4LNG_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3e37RCSB PDB    PDBbindED5

Entry Information
PDB ID4lnb
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameCaaX farnesyltransferase alpha subunit Ram2
Ligand NameED5
EC.Number E.C.2.5.1.58
Resolution 1.75(Å)
Affinity (Kd/Ki/IC50)IC50=275nM
Release Year2014
Protein/NA SequenceCheck fasta file
Primary Reference (2014) Protein Sci. Vol. 23: pp. 289-301
Ligand Properties
Formula C32H44N6O4S
Molecular Weight 608.795
Exact Mass 608.314
No. of atoms 87
No. of bonds 90
Polar Surface Area 120.21
LOGP Value 4.06      (Computed with XLOGP3)
6.19      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 0
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 14
No. of Nitrogen and Oxygen Atoms: 10
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q4WP27  Q4WPS9  
Entrez Gene IDNCBI Entrez Gene ID: 3509633  3509030  
ASDInformation of known allosteric effects of PDB entries

 
This site has been visited times since Nov 2007.


Copyright ©2007-2024    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝e湪鐢宠涓


Technical Support锛堟妧鏈敮鎸侊級: yingsaisi@foxmail.com