Browse entries in the PDBbind-CN Database

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Related entries of code: 4u0i
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1t46RCSB PDB    PDBbind313aa, >1T46_1|Chain... at 100%
3g0eRCSB PDB    PDBbind336aa, >3G0E_1|Chain... *
3g0fRCSB PDB    PDBbind336aa, >3G0F_1|Chains... at 99%
4hvsRCSB PDB    PDBbind335aa, >4HVS_1|Chain... at 92%
6gqmRCSB PDB    PDBbind328aa, >6GQM_1|Chains... at 90%
6mobRCSB PDB    PDBbind312aa, >6MOB_1|Chain... at 100%
6klaRCSB PDB    PDBbind331aa, >6KLA_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3ik3RCSB PDB    PDBbind0LI
3oxzRCSB PDB    PDBbind0LI
3zosRCSB PDB    PDBbind0LI
4qrcRCSB PDB    PDBbind0LI
4uxqRCSB PDB    PDBbind0LI
4v01RCSB PDB    PDBbind0LI
4v04RCSB PDB    PDBbind0LI
6eg9RCSB PDB    PDBbind0LI

Entry Information
PDB ID4u0i
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor KIT
Ligand Name0LI
EC.Number E.C.2.7.10.1
Resolution 2(Å)
Affinity (Kd/Ki/IC50)IC50=6nM
Release Year2014
Protein/NA SequenceCheck fasta file
Primary Reference (2014) Clin.Cancer Res. Vol. 20: pp. 5745-5755
Ligand Properties
Formula C29H29F3N6O
Molecular Weight 534.575
Exact Mass 534.235
No. of atoms 68
No. of bonds 72
Polar Surface Area 68.17
LOGP Value 4.11      (Computed with XLOGP3)
4.83      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P10721  
Entrez Gene IDNCBI Entrez Gene ID: 3815  
ASDInformation of known allosteric effects of PDB entries

 
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