Browse entries in the PDBbind-CN Database

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Related entries of code: 5ei4
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2yelRCSB PDB    PDBbind127aa, >2YEL:A|PDBID|CHAIN|... at 98%
2yemRCSB PDB    PDBbind130aa, >2YEM:B|PDBID|CHAIN|... at 98%
3jvkRCSB PDB    PDBbind131aa, >3JVK:A|PDBID|CHAIN|... at 95%
3mukRCSB PDB    PDBbind131aa, >3MUK:A|PDBID|CHAIN|... at 95%
3mxfRCSB PDB    PDBbind127aa, >3MXF:A|PDBID|CHAIN|... at 98%
3p5oRCSB PDB    PDBbind127aa, >3P5O:A|PDBID|CHAIN|... at 98%
3u5jRCSB PDB    PDBbind127aa, >3U5J:A|PDBID|CHAIN|... at 98%
3u5lRCSB PDB    PDBbind127aa, >3U5L:A|PDBID|CHAIN|... at 98%
3zyuRCSB PDB    PDBbind127aa, >3ZYU:B|PDBID|CHAIN|... at 98%
4bw1RCSB PDB    PDBbind127aa, >4BW1:A|PDBID|CHAIN|... at 98%
4bw2RCSB PDB    PDBbind127aa, >4BW2:A|PDBID|CHAIN|... at 98%
4bw3RCSB PDB    PDBbind127aa, >4BW3:A|PDBID|CHAIN|... at 98%
4bw4RCSB PDB    PDBbind127aa, >4BW4:A|PDBID|CHAIN|... at 98%
4c66RCSB PDB    PDBbind126aa, >4C66:A|PDBID|CHAIN|... at 98%
4cflRCSB PDB    PDBbind127aa, >4CFL:A|PDBID|CHAIN|... at 98%
4cl9RCSB PDB    PDBbind127aa, >4CL9:A|PDBID|CHAIN|... at 98%
4clbRCSB PDB    PDBbind127aa, >4CLB:A|PDBID|CHAIN|... at 98%
4e96RCSB PDB    PDBbind127aa, >4E96:A|PDBID|CHAIN|... at 98%
4f3iRCSB PDB    PDBbind127aa, >4F3I:A|PDBID|CHAIN|... at 98%
4hbvRCSB PDB    PDBbind127aa, >4HBV:A|PDBID|CHAIN|... at 98%
4hbwRCSB PDB    PDBbind127aa, >4HBW:A|PDBID|CHAIN|... at 97%
4hbxRCSB PDB    PDBbind127aa, >4HBX:A|PDBID|CHAIN|... at 98%
4hbyRCSB PDB    PDBbind127aa, >4HBY:A|PDBID|CHAIN|... at 98%
4hxlRCSB PDB    PDBbind125aa, >4HXL:A|PDBID|CHAIN|... at 99%
4hxmRCSB PDB    PDBbind124aa, >4HXM:A|PDBID|CHAIN|... at 99%
4hxrRCSB PDB    PDBbind125aa, >4HXR:A|PDBID|CHAIN|... at 99%
4hxsRCSB PDB    PDBbind124aa, >4HXS:A|PDBID|CHAIN|... at 99%
4j0rRCSB PDB    PDBbind127aa, >4J0R:A|PDBID|CHAIN|... at 98%
4j0sRCSB PDB    PDBbind127aa, >4J0S:A|PDBID|CHAIN|... at 98%
4j3iRCSB PDB    PDBbind127aa, >4J3I:A|PDBID|CHAIN|... at 98%
4lysRCSB PDB    PDBbind126aa, >4LYS:A|PDBID|CHAIN|... at 99%
4lywRCSB PDB    PDBbind127aa, >4LYW:A|PDBID|CHAIN|... at 98%
4lzrRCSB PDB    PDBbind127aa, >4LZR:A|PDBID|CHAIN|... at 96%
4lzsRCSB PDB    PDBbind127aa, >4LZS:A|PDBID|CHAIN|... at 98%
4menRCSB PDB    PDBbind127aa, >4MEN:A|PDBID|CHAIN|... at 98%
4meoRCSB PDB    PDBbind127aa, >4MEO:A|PDBID|CHAIN|... at 98%
4mepRCSB PDB    PDBbind127aa, >4MEP:A|PDBID|CHAIN|... at 98%
4meqRCSB PDB    PDBbind127aa, >4MEQ:A|PDBID|CHAIN|... at 98%
4mr3RCSB PDB    PDBbind127aa, >4MR3:A|PDBID|CHAIN|... at 98%
4mr4RCSB PDB    PDBbind127aa, >4MR4:A|PDBID|CHAIN|... at 98%
4nucRCSB PDB    PDBbind127aa, >4NUC:A|PDBID|CHAIN|... at 98%
4nudRCSB PDB    PDBbind127aa, >4NUD:A|PDBID|CHAIN|... at 98%
4nueRCSB PDB    PDBbind127aa, >4NUE:A|PDBID|CHAIN|... at 98%
4o70RCSB PDB    PDBbind127aa, >4O70:B|PDBID|CHAIN|... at 98%
4o71RCSB PDB    PDBbind127aa, >4O71:B|PDBID|CHAIN|... at 98%
4o72RCSB PDB    PDBbind127aa, >4O72:A|PDBID|CHAIN|... at 98%
4o74RCSB PDB    PDBbind127aa, >4O74:B|PDBID|CHAIN|... at 98%
4o75RCSB PDB    PDBbind127aa, >4O75:A|PDBID|CHAIN|... at 98%
4o76RCSB PDB    PDBbind127aa, >4O76:D|PDBID|CHAIN|... at 98%
4o77RCSB PDB    PDBbind127aa, >4O77:B|PDBID|CHAIN|... at 98%
4o78RCSB PDB    PDBbind127aa, >4O78:A|PDBID|CHAIN|... at 98%
4o7aRCSB PDB    PDBbind127aa, >4O7A:A|PDBID|CHAIN|... at 98%
4o7bRCSB PDB    PDBbind127aa, >4O7B:A|PDBID|CHAIN|... at 98%
4o7cRCSB PDB    PDBbind127aa, >4O7C:A|PDBID|CHAIN|... at 98%
4o7eRCSB PDB    PDBbind127aa, >4O7E:B|PDBID|CHAIN|... at 98%
4o7fRCSB PDB    PDBbind127aa, >4O7F:B|PDBID|CHAIN|... at 98%
4ogiRCSB PDB    PDBbind127aa, >4OGI:B|PDBID|CHAIN|... at 98%
4ogjRCSB PDB    PDBbind127aa, >4OGJ:B|PDBID|CHAIN|... at 98%
4pceRCSB PDB    PDBbind127aa, >4PCE:A|PDBID|CHAIN|... at 98%
4pciRCSB PDB    PDBbind127aa, >4PCI:A|PDBID|CHAIN|... at 98%
4ps5RCSB PDB    PDBbind127aa, >4PS5:B|PDBID|CHAIN|... at 98%
4qb3RCSB PDB    PDBbind127aa, >4QB3:A|PDBID|CHAIN|... at 98%
4qr3RCSB PDB    PDBbind125aa, >4QR3:A|PDBID|CHAIN|... at 98%
4qr4RCSB PDB    PDBbind125aa, >4QR4:A|PDBID|CHAIN|... at 98%
4qr5RCSB PDB    PDBbind125aa, >4QR5:A|PDBID|CHAIN|... at 98%
4qzsRCSB PDB    PDBbind127aa, >4QZS:A|PDBID|CHAIN|... at 98%
4uixRCSB PDB    PDBbind127aa, >4UIX:C|PDBID|CHAIN|... at 97%
4uiyRCSB PDB    PDBbind127aa, >4UIY:A|PDBID|CHAIN|... at 98%
4uizRCSB PDB    PDBbind127aa, >4UIZ:A|PDBID|CHAIN|... at 98%
4uydRCSB PDB    PDBbind153aa, >4UYD:A|PDBID|CHAIN|... at 91%
4wivRCSB PDB    PDBbind127aa, >4WIV:A|PDBID|CHAIN|... at 98%
4x2iRCSB PDB    PDBbind126aa, >4X2I:A|PDBID|CHAIN|... at 97%
4xy9RCSB PDB    PDBbind127aa, >4XY9:A|PDBID|CHAIN|... at 98%
4xyaRCSB PDB    PDBbind127aa, >4XYA:A|PDBID|CHAIN|... at 98%
4yh3RCSB PDB    PDBbind129aa, >4YH3:A|PDBID|CHAIN|... at 98%
4yh4RCSB PDB    PDBbind129aa, >4YH4:A|PDBID|CHAIN|... at 98%
4z1qRCSB PDB    PDBbind127aa, >4Z1Q:B|PDBID|CHAIN|... at 97%
4z1sRCSB PDB    PDBbind126aa, >4Z1S:B|PDBID|CHAIN|... at 97%
4z93RCSB PDB    PDBbind112aa, >4Z93:A|PDBID|CHAIN|... at 100%
5a5sRCSB PDB    PDBbind127aa, >5A5S:A|PDBID|CHAIN|... at 97%
5a85RCSB PDB    PDBbind127aa, >5A85:A|PDBID|CHAIN|... at 98%
5acyRCSB PDB    PDBbind127aa, >5ACY:B|PDBID|CHAIN|... at 98%
5d24RCSB PDB    PDBbind126aa, >5D24:A|PDBID|CHAIN|... at 99%
5d25RCSB PDB    PDBbind126aa, >5D25:A|PDBID|CHAIN|... at 99%
5d26RCSB PDB    PDBbind127aa, >5D26:A|PDBID|CHAIN|... at 98%
5d3hRCSB PDB    PDBbind126aa, >5D3H:A|PDBID|CHAIN|... at 99%
5d3jRCSB PDB    PDBbind126aa, >5D3J:A|PDBID|CHAIN|... at 99%
5d3lRCSB PDB    PDBbind127aa, >5D3L:A|PDBID|CHAIN|... at 98%
5d3nRCSB PDB    PDBbind126aa, >5D3N:A|PDBID|CHAIN|... at 99%
5d3pRCSB PDB    PDBbind127aa, >5D3P:A|PDBID|CHAIN|... at 98%
5d3sRCSB PDB    PDBbind126aa, >5D3S:A|PDBID|CHAIN|... at 99%
5d3tRCSB PDB    PDBbind127aa, >5D3T:A|PDBID|CHAIN|... at 98%
5dlxRCSB PDB    PDBbind127aa, >5DLX:A|PDBID|CHAIN|... at 98%
5dlzRCSB PDB    PDBbind127aa, >5DLZ:A|PDBID|CHAIN|... at 98%
5dw2RCSB PDB    PDBbind129aa, >5DW2:A|PDBID|CHAIN|... at 98%
5dx4RCSB PDB    PDBbind127aa, >5DX4:A|PDBID|CHAIN|... at 98%
5eguRCSB PDB    PDBbind127aa, >5EGU:D|PDBID|CHAIN|... at 98%
5eisRCSB PDB    PDBbind127aa, >5EIS:A|PDBID|CHAIN|... at 98%
5f5zRCSB PDB    PDBbind127aa, >5F5Z:A|PDBID|CHAIN|... at 98%
5f60RCSB PDB    PDBbind127aa, >5F60:A|PDBID|CHAIN|... at 98%
5f61RCSB PDB    PDBbind127aa, >5F61:B|PDBID|CHAIN|... at 98%
5f62RCSB PDB    PDBbind127aa, >5F62:A|PDBID|CHAIN|... at 98%
5f63RCSB PDB    PDBbind127aa, >5F63:A|PDBID|CHAIN|... at 98%
5hclRCSB PDB    PDBbind127aa, >5HCL:A|PDBID|CHAIN|... at 98%
5hlsRCSB PDB    PDBbind128aa, >5HLS:A|PDBID|CHAIN|... at 97%
5hm0RCSB PDB    PDBbind128aa, >5HM0:A|PDBID|CHAIN|... at 97%
5i80RCSB PDB    PDBbind126aa, >5I80:A|PDBID|CHAIN|... at 98%
5i88RCSB PDB    PDBbind126aa, >5I88:A|PDBID|CHAIN|... at 98%
5igkRCSB PDB    PDBbind127aa, >5IGK:A|PDBID|CHAIN|... at 98%
5khmRCSB PDB    PDBbind127aa, >5KHM:B|PDBID|CHAIN|... at 98%
5kj0RCSB PDB    PDBbind127aa, >5KJ0:A|PDBID|CHAIN|... at 98%
5ku3RCSB PDB    PDBbind126aa, >5KU3:A|PDBID|CHAIN|... at 98%
5lj1RCSB PDB    PDBbind127aa, >5LJ1:A|PDBID|CHAIN|... at 98%
5lj2RCSB PDB    PDBbind127aa, >5LJ2:A|PDBID|CHAIN|... at 98%
5luuRCSB PDB    PDBbind127aa, >5LUU:A|PDBID|CHAIN|... at 98%
5m39RCSB PDB    PDBbind127aa, >5M39:B|PDBID|CHAIN|... at 98%
5m3aRCSB PDB    PDBbind127aa, >5M3A:A|PDBID|CHAIN|... at 98%
5mkzRCSB PDB    PDBbind127aa, >5MKZ:A|PDBID|CHAIN|... at 98%
5mliRCSB PDB    PDBbind127aa, >5MLI:A|PDBID|CHAIN|... at 98%
5ti2RCSB PDB    PDBbind127aa, >5TI2:A|PDBID|CHAIN|... at 98%
5ti3RCSB PDB    PDBbind127aa, >5TI3:A|PDBID|CHAIN|... at 98%
5ti4RCSB PDB    PDBbind127aa, >5TI4:A|PDBID|CHAIN|... at 98%
5ti5RCSB PDB    PDBbind127aa, >5TI5:A|PDBID|CHAIN|... at 98%
5ti6RCSB PDB    PDBbind127aa, >5TI6:A|PDBID|CHAIN|... at 98%
5ti7RCSB PDB    PDBbind127aa, >5TI7:A|PDBID|CHAIN|... at 98%
5u28RCSB PDB    PDBbind138aa, >5U28:A|PDBID|CHAIN|... at 99%
5u2cRCSB PDB    PDBbind124aa, >5U2C:B|PDBID|CHAIN|... at 95%
5u2eRCSB PDB    PDBbind140aa, >5U2E:B|PDBID|CHAIN|... at 97%
5u2fRCSB PDB    PDBbind140aa, >5U2F:B|PDBID|CHAIN|... at 97%
5ueuRCSB PDB    PDBbind109aa, >5UEU:B|PDBID|CHAIN|... at 97%
5uexRCSB PDB    PDBbind109aa, >5UEX:A|PDBID|CHAIN|... at 97%
5ueyRCSB PDB    PDBbind109aa, >5UEY:A|PDBID|CHAIN|... at 97%
5uezRCSB PDB    PDBbind109aa, >5UEZ:A|PDBID|CHAIN|... at 97%
5uf0RCSB PDB    PDBbind109aa, >5UF0:A|PDBID|CHAIN|... at 97%
5ulaRCSB PDB    PDBbind127aa, >5ULA:B|PDBID|CHAIN|... at 98%
5uooRCSB PDB    PDBbind131aa, >5UOO:A|PDBID|CHAIN|... at 97%
5y1yRCSB PDB    PDBbind125aa, >5Y1Y:A|PDBID|CHAIN|... at 99%
6afrRCSB PDB    PDBbind127aa, >6AFR:A|PDBID|CHAIN|... at 98%
6boyRCSB PDB    PDBbind127aa, >6BOY:C|PDBID|CHAIN|... at 98%
6c7qRCSB PDB    PDBbind131aa, >6C7Q:A|PDBID|CHAIN|... at 97%
6c7rRCSB PDB    PDBbind125aa, >6C7R:A|PDBID|CHAIN|... at 97%
6cd4RCSB PDB    PDBbind127aa, >6CD4:A|PDBID|CHAIN|... at 98%
6cisRCSB PDB    PDBbind125aa, >6CIS:A|PDBID|CHAIN|... at 98%
6ciyRCSB PDB    PDBbind127aa, >6CIY:A|PDBID|CHAIN|... at 98%
6cj1RCSB PDB    PDBbind125aa, >6CJ1:A|PDBID|CHAIN|... at 98%
6ckrRCSB PDB    PDBbind126aa, >6CKR:B|PDBID|CHAIN|... at 99%
6cksRCSB PDB    PDBbind126aa, >6CKS:A|PDBID|CHAIN|... at 99%
6czuRCSB PDB    PDBbind129aa, >6CZU:A|PDBID|CHAIN|... at 98%
6czvRCSB PDB    PDBbind129aa, >6CZV:A|PDBID|CHAIN|... at 98%
6djcRCSB PDB    PDBbind132aa, >6DJC:B|PDBID|CHAIN|... at 98%
6dneRCSB PDB    PDBbind434aa, >6DNE:B|PDBID|CHAIN|... at 100%
6e4aRCSB PDB    PDBbind129aa, >6E4A:B|PDBID|CHAIN|... at 98%
6fnxRCSB PDB    PDBbind127aa, >6FNX:A|PDBID|CHAIN|... at 98%
6fo5RCSB PDB    PDBbind127aa, >6FO5:A|PDBID|CHAIN|... at 98%
6hdqRCSB PDB    PDBbind127aa, >6HDQ:A|PDBID|CHAIN|... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID5ei4
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namefirst bromodomain of the human BRD4 protein, BRD4(BD1)
Ligand Name5NV
EC.Number E.C.-.-.-.-
Resolution 1.05(Å)
Affinity (Kd/Ki/IC50)IC50=26.4uM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2016) J.Med.Chem. Vol. 59: pp. 1634-1641
Ligand Properties
Formula C17H18ClN8O2S
Molecular Weight 433.895
Exact Mass 433.096
No. of atoms 47
No. of bonds 50
Polar Surface Area 168.04
LOGP Value 3.56      (Computed with XLOGP3)
-0.39      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 10
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): O60885  
Entrez Gene IDNCBI Entrez Gene ID: 23476  
ASDInformation of known allosteric effects of PDB entries

 
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