Browse entries in the PDBbind-CN Database

Display Options: Structure:  




Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

           
Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 5h8x
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1a85RCSB PDB    PDBbind158aa, >1A85_1|Chain... at 100%
1a86RCSB PDB    PDBbind158aa, >1A86_1|Chain... at 100%
1bzsRCSB PDB    PDBbind165aa, >1BZS_1|Chain... *
1jaoRCSB PDB    PDBbind163aa, >1JAO_1|Chain... at 100%
1jaqRCSB PDB    PDBbind163aa, >1JAQ_1|Chain... at 100%
1jh1RCSB PDB    PDBbind158aa, >1JH1_1|Chain... at 100%
1jj9RCSB PDB    PDBbind163aa, >1JJ9_1|Chain... at 100%
1mncRCSB PDB    PDBbind163aa, >1MNC_1|Chain... at 97%
1zp5RCSB PDB    PDBbind163aa, >1ZP5_1|Chain... at 100%
1zs0RCSB PDB    PDBbind163aa, >1ZS0_1|Chain... at 100%
1zvxRCSB PDB    PDBbind163aa, >1ZVX_1|Chain... at 100%
3dngRCSB PDB    PDBbind163aa, >3DNG_1|Chains... at 100%
3dpeRCSB PDB    PDBbind163aa, >3DPE_1|Chain... at 100%
3dpfRCSB PDB    PDBbind163aa, >3DPF_1|Chains... at 100%
3tt4RCSB PDB    PDBbind159aa, >3TT4_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID5h8x
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMatrix metalloproteinases, MMP-8
Ligand Name5XT
EC.Number E.C.3.4.24.34
Resolution 1.3(Å)
Affinity (Kd/Ki/IC50)IC50=3.1uM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2016) J Enzyme Inhib Med Chem Vol. 31: pp. 25-37
Ligand Properties
Formula C18H15NO4S
Molecular Weight 341.381
Exact Mass 341.072
No. of atoms 39
No. of bonds 41
Polar Surface Area 95.01
LOGP Value 3.36      (Computed with XLOGP3)
4.72      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P22894  
Entrez Gene IDNCBI Entrez Gene ID: 4317  
ASDInformation of known allosteric effects of PDB entries

 
This site has been visited times since Nov 2007.


Copyright ©2007-2024    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝e湪鐢宠涓


Technical Support锛堟妧鏈敮鎸侊級: yingsaisi@foxmail.com