Browse entries in the PDBbind-CN Database

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Related entries of code: 5l2w
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
No similar entries are found!
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
4kcxRCSB PDB    PDBbind1QK
4o70RCSB PDB    PDBbind1QK
6gu6RCSB PDB    PDBbind1QK

Entry Information
PDB ID5l2w
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namehuman Cyclin-dependent kinase 6, CDK6
Ligand Name1QK
EC.Number E.C.2.7.11.22
Resolution 2.8(Å)
Affinity (Kd/Ki/IC50)Kd=210nM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2016) Mol.Cancer Ther. Vol. 15: pp. 2273-2281
Ligand Properties
Formula C21H30N6O2
Molecular Weight 398.502
Exact Mass 398.243
No. of atoms 59
No. of bonds 62
Polar Surface Area 89.16
LOGP Value 2.39      (Computed with XLOGP3)
2.67      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 9
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P24864  P24941  
Entrez Gene IDNCBI Entrez Gene ID: 898  1017  
ASDInformation of known allosteric effects of PDB entries

 
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