Browse entries in the PDBbind-CN Database

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Related entries of code: 5mkx
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1wugRCSB PDB    PDBbind118aa, >1WUG_1|Chain... at 96%
1wumRCSB PDB    PDBbind118aa, >1WUM_1|Chain... at 96%
5fdzRCSB PDB    PDBbind119aa, >5FDZ_1|Chains... at 100%
5fe6RCSB PDB    PDBbind119aa, >5FE6_1|Chains... at 100%
5fe7RCSB PDB    PDBbind119aa, >5FE7_1|Chains... at 100%
5fe9RCSB PDB    PDBbind119aa, >5FE9_1|Chains... at 100%
5lvqRCSB PDB    PDBbind119aa, >5LVQ_1|Chains... at 100%
5lvrRCSB PDB    PDBbind119aa, >5LVR_1|Chains... at 100%
5ml0RCSB PDB    PDBbind110aa, >5ML0_1|Chain... at 91%
6j3oRCSB PDB    PDBbind140aa, >6J3O_1|Chains... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
5mliRCSB PDB    PDBbind82I

Entry Information
PDB ID5mkx
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameHistone acetyltransferase KAT2B
Ligand Name82I
EC.Number E.C.2.3.1.48
Resolution 1.68(Å)
Affinity (Kd/Ki/IC50)IC50=20uM
Release Year2017
Protein/NA SequenceCheck fasta file
Primary Reference (2017) J. Med. Chem. Vol. 60: pp. 695-709
Ligand Properties
Formula C6H8ClN3O
Molecular Weight 173.600
Exact Mass 173.036
No. of atoms 19
No. of bonds 19
Polar Surface Area 45.03
LOGP Value 0.18      (Computed with XLOGP3)
-0.50      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 0
No. of Hydrogen Bond Acceptors: 1
No. of Rotatable Bonds: 0
No. of Nitrogen and Oxygen Atoms: 4
No. of Rings: 1
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q92831  
Entrez Gene IDNCBI Entrez Gene ID: 8850  
ASDInformation of known allosteric effects of PDB entries

 
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