Browse entries in the PDBbind-CN Database

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Related entries of code: 5tuy
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3k5kRCSB PDB    PDBbind283aa, >3K5K_1|Chains... at 99%
3rjwRCSB PDB    PDBbind283aa, >3RJW_1|Chains... at 99%
4nvqRCSB PDB    PDBbind285aa, >4NVQ_1|Chains... *
5ttfRCSB PDB    PDBbind283aa, >5TTF_1|Chains... at 99%
5vscRCSB PDB    PDBbind275aa, >5VSC_1|Chains... at 100%
5vseRCSB PDB    PDBbind275aa, >5VSE_1|Chains... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
5tuzRCSB PDB    PDBbind7L6

Entry Information
PDB ID5tuy
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameHistone-lysine N-methyltransferase EHMT2
Ligand Name7L6
EC.Number E.C.-.-.-.-
Resolution 2.6(Å)
Affinity (Kd/Ki/IC50)Kd=445nM
Release Year2017
Protein/NA SequenceCheck fasta file
Primary Reference (2017) J. Med. Chem. Vol. 60: pp. 1876-1891
Ligand Properties
Formula C20H30N5O3
Molecular Weight 388.484
Exact Mass 388.235
No. of atoms 58
No. of bonds 61
Polar Surface Area 73.18
LOGP Value 2.48      (Computed with XLOGP3)
2.28      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 5
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q96KQ7  
Entrez Gene IDNCBI Entrez Gene ID: 10919  
ASDInformation of known allosteric effects of PDB entries

 
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